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Prevalence and determinants of post-stroke sleep disorders: a cross-sectional hospital-based study

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Abstract

Introduction

Post-stroke sleep disorders (PSSD) are an important part of post-stroke disability. PSSD is neglected as a part of stroke rehabilitation. We aimed to study the prevalence and determinants of PSSD in a hospital based, single center setting.

Methods

In a cross-sectional study, adult patients (≥ 18 years) with stroke (one month to one year after the onset), were enrolled in the study. Demographic, clinical, radiological, and motor and functional disabilities were assessed. Sleep quality was assessed with Pittsburg Sleep Quality Index (PSQI) and STOP BANG questionnaire (for obstructive sleep apnea [OSA]). Patients with poor sleep quality (PSQI > 5) were analyzed for risk factors.

Results

A total of 103 patients were recruited in the study period (January 2021 to June 2022). The self-reported prevalence of PSSD was 16% which increased to 72% when the PSQI was administered. High risk of OSA was present in 33%. In bivariate analysis, factors associated with PSQI > 5 were involvement of ≥ 2 lobes, lower body mass index (BMI), worse modified Rankin Scale (mRS), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A) and Stroke Specific Quality of Life (SSQoL). In multivariate analysis, only depression was associated with PSQI > 5 (OR: 1.3 (1.0; 1.7); p-value = 0.03).

Conclusion

PSSD had a prevalence of 72%. In multivariate analysis, the factor associated with PSQI > 5 was worse HAM-D score.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Authors and Affiliations

  1. Neurosciences Center, Department of Neurology, All India Institute of Medical Sciences, Room number 707, 7th Floor, New Delhi, India

    Kamalesh Tayade, Deepti Vibha, Rajesh Kumar Singh, Awadh Kishor Pandit, Bhargavi Ramanujam, Animesh Das, Arunmozhimaran Elavarasi, Ayush Agarwal, Achal Kumar Srivastava & Manjari Tripathi

Authors
  1. Kamalesh Tayade
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  2. Deepti Vibha
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  3. Rajesh Kumar Singh
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  4. Awadh Kishor Pandit
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  7. Arunmozhimaran Elavarasi
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  9. Achal Kumar Srivastava
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Corresponding author

Correspondence to Deepti Vibha.

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All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers' bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Statement for ethical clearance

The Institutional Review Board (IRB) of the All India Institute of Medical Sciences (AIIMS), New Delhi, approved the study (Reference no. IECPG-557/21.10.2020, RT-11/25.11.2020).

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Tayade, K., Vibha, D., Singh, R.K. et al. Prevalence and determinants of post-stroke sleep disorders: a cross-sectional hospital-based study. Sleep Breath 27, 2429–2433 (2023). https://doi.org/10.1007/s11325-023-02850-z

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  • DOI: https://doi.org/10.1007/s11325-023-02850-z

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