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Meta-analysis of correlation between sleep duration and gender difference in adults with type 2 diabetes

  • Sleep Breathing Physiology and Disorders • Original Article
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Abstract

Objective

To explore the correlation between sleep duration and type II diabetes in adults.

Method

Computer databases searches were carried out through October 1, 2022, including PubMed, Cochrane Library, Embase, and Web of Science. Relevant literature was collected, and the Newcastle–Ottawa Scale (NOS) and extracted data were used to exclude studies and evaluate quality on the basis of inclusion and exclusion criteria. Meta-analysis was conducted using RevMan 5.4.1 software with random/fixed effects models.

Results

A total of 5 studies with 74,226 subjects (31,611 in the male study group, 42,615 in the female study group) were included. The meta-analysis revealed that women with long sleep duration (LSD) have a higher risk for developing type II diabetes than men, OR = 0.70; 95% CI 0.59–0.84, Z = 4.00 and P < 0.001. Men with short sleep duration (SSD) tended to have a higher risk in developing type II diabetes than women though the difference between men and women did not reach statistical significance, OR = 1.09, 95% CI 0.73–1.62, Z = 0.42 and P = 0.68. Further subgroup analysis by regional populations suggested that men in Europe and America with SSD had a higher risk of type II diabetes OR = 1.52, 95% CI 1.04–2.21, Z = 2.18 and P = 0.03.

Conclusion

Women with LSD may have a higher risk for type II diabetes, and men in Europe and America with SSD may have a higher risk for type II diabetes than men of other regions.

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Data availability

The data used to support the findings of this study are available from the corresponding author upon request.

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Acknowledgements

We would also like to thank everyone who has helped with our research.

Funding

This study was funded by the Natural Science Foundation of Guangdong Province (2019A1515010981).

Author information

Author notes

  1. Chaoyu Wang, Yanhong Liu, Xiaojuan Chen, and Jinru Zhu contributed equally to this work.

Authors and Affiliations

  1. Taishan Hospital of Traditional Chinese Medicine, Jiangmen, China

    Chaoyu Wang & Yanhong Liu

  2. Medical College of Jiaying University, Meizhou, China

    Xiaojuan Chen

  3. The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524003, Guangdong, China

    Jinru Zhu, Huimin Chen & Zhenzhen Zheng

  4. Central People’s Hospital of Zhanjiang, Zhanjiang, China

    Qinglan Wu

  5. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China

    Huizhao Liao, Junyan Lin, Zhiwei Wang & Riken Chen

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  1. Chaoyu Wang
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Contributions

RC, CW, YL, ZZZ, XC, and JZ are the guarantor of the manuscript and take responsibility for the content of this manuscript. RC, ZZ, and CW contributed to the design of the study. HC and JL were involved in the data analysis. HL and ZW contributed to the acquisition of primary data. ZZZ, CW, and XC wrote the initial draft of the manuscript. RC and YL contributed significantly to the revision of the manuscript. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Zhenzhen Zheng or Riken Chen.

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Wang, C., Liu, Y., Chen, X. et al. Meta-analysis of correlation between sleep duration and gender difference in adults with type 2 diabetes. Sleep Breath 27, 2325–2332 (2023). https://doi.org/10.1007/s11325-023-02841-0

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  • DOI: https://doi.org/10.1007/s11325-023-02841-0

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