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Can we enhance compliance to treatment by performing a continuous positive airway pressure trial in obstructive sleep apnea?

  • Sleep Breathing Physiology and Disorders • Original Article
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Abstract

Background

Although continuous positive airway pressure (CPAP) therapy is the most effective treatment for obstructive sleep apnea (OSA), it is not always easy to gain adherence to therapy. We aimed to evaluate how short-term CPAP application during the daytime before the titration night affects polysomnographic data and CPAP adherence in OSA.

Methods

Patients with moderate to severe OSA for whom CPAP titration was recommended were prospectively randomized to daytime CPAP application (group 1) or usual care (group 2).  For group 1, CPAP was applied for 30–60 min in daytime conditions to acclimate patients to the device. An appointment was then made to perform CPAP titration with PSG. In group 2 (usual care), the first CPAP application was performed on the titration night. PSG recordings and titration night recordings of both groups were compared. All subjects were evaluated 1 month after the initiation of CPAP treatment.

Results

Among 246 cases, first night data were similar in both groups. During the titration night, total sleep time, sleep efficiency, and time in stage N3 were significantly higher in patients who underwent the daytime CPAP trial. Adherence to CPAP treatment at first-month follow-up was significantly higher in the group 1 (5.7 ± 1.0 h/night) compared to the group 2 (3.9 ± 1.1 h/night, p < 0.001).

Conclusion

A short-term daytime CPAP trial in patients before the titration night may provide longer and more efficient sleep on the titration night and better CPAP adherence at one month.

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Authors and Affiliations

  1. Department of Chest Diseases, Health Sciences University, Kartal Dr Lutfi Kırdar City Hospital, Istanbul, Turkey

    Elif Torun Parmaksız

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  1. Elif Torun Parmaksız
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Correspondence to Elif Torun Parmaksız.

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Ethics approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study protocol was approved by the local ethics committee (Kartal Dr. Lutfi Kirdar Ethics Committee Approval number: 514/190/12)

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Informed consent was obtained from all individual participants included in the study.

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The author declares no competing interest.

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Parmaksız, E.T. Can we enhance compliance to treatment by performing a continuous positive airway pressure trial in obstructive sleep apnea?. Sleep Breath 25, 2039–2043 (2021). https://doi.org/10.1007/s11325-021-02340-0

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  • DOI: https://doi.org/10.1007/s11325-021-02340-0

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