Sleep and Breathing

, Volume 21, Issue 4, pp 909–917 | Cite as

Assessing the likelihood of obstructive sleep apnea: a comparison of nine screening questionnaires

  • Kuruswamy Thurai Prasad
  • Inderpaul Singh Sehgal
  • Ritesh Agarwal
  • Ashutosh Nath Aggarwal
  • Digambar Behera
  • Sahajal Dhooria
Sleep Breathing Physiology and Disorders • Original Article
  • 439 Downloads

Abstract

Purpose

Several questionnaires are available for the screening of obstructive sleep apnea (OSA). Herein, we compare the performance characteristics of nine available questionnaires for assessing the likelihood of OSA.

Methods

Consecutive subjects who underwent polysomnography at the sleep laboratory of the unit were included. Subjects with obstructive events and apnea hypopnea index (AHI) ≥5 were considered to have OSA. The likelihood ratios (LRs) and other performance characteristics were calculated for the following nine questionnaires: Berlin, modified Berlin, STOP, STOP-Bang and OSA50 questionnaires, sleep apnea clinical score (SACS), Epworth sleepiness scale (ESS), American Society of Anesthesiologists (ASA) checklist, and the elbow sign questionnaire.

Results

Two-hundred and ten subjects (mean age, 46.5 years; mean body mass index [BMI], 31.9 kg/m2; 27.1% women) were included. OSA was diagnosed in 78.1% of patients; 49.5% had severe OSA (AHI ≥30). The SACS questionnaire had the highest positive LR (LR+, 5.6) and positive predictive value (95.2%). The modified Berlin questionnaire had the best negative LR (LR−, 0.2) and the highest negative predictive value (57.1%). The STOP-Bang questionnaire also had an LR− of 0.2 if BMI threshold of 25 kg/m2 (like that in the modified Berlin questionnaire) was used. Among individual items of various sleep questionnaires, the highest LR+ was obtained for neck circumference >43 cm (LR+, 4.9), while the best LR− was obtained for snoring and BMI >25 kg/m2 (LR−, 0.2).

Conclusions

The SACS and the STOP-Bang questionnaires (BMI threshold of 25 kg/m2) were found to provide the best positive and negative LRs, respectively, for the prediction of OSA. We believe that information from these questionnaires may help in prioritizing patients for sleep studies in high-volume centers.

Keywords

Sleep disordered breathing Sleep apnea OSA Questionnaire Screening 

Notes

Acknowledgements

We thank Dr. V. Nagarjuna Maturu for his inputs at the time of designing of this study.

Authors’ contributions

KTP: data collection, analysis, initial drafting, and final approval of the manuscript

ISS: data collection, analysis, initial drafting, and final approval of the manuscript

RA: data collection, analysis, initial drafting, and final approval of the manuscript

ANA: data collection, analysis, initial drafting, and final approval of the manuscript

DB: data collection, analysis, initial drafting, and final approval of the manuscript

SD: involved in conception, data collection, analysis, initial drafting, and final approval of the manuscript, guarantor of the overall content

Compliance with ethical standards

Funding

No funding was received for this research.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study for performing the procedure.

Supplementary material

11325_2017_1495_MOESM1_ESM.docx (14 kb)
ESM 1 (DOCX 13 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Kuruswamy Thurai Prasad
    • 1
  • Inderpaul Singh Sehgal
    • 1
  • Ritesh Agarwal
    • 1
  • Ashutosh Nath Aggarwal
    • 1
  • Digambar Behera
    • 1
  • Sahajal Dhooria
    • 1
  1. 1.Department of Pulmonary MedicinePostgraduate Institute of Medical Education and ResearchChandigarhIndia

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