Sleepiness and sleep-disordered breathing during pregnancy
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This study aimed to examine if there is a difference in the prevalence of obstructive sleep apnea (OSA) and sleepiness between pregnant and non-pregnant women. It also aimed to evaluate if obstetric outcomes were associated to sleep-disordered breathing among the pregnant women.
One hundred pregnant women (gestational weeks 24–34) and 80 age- and body mass index-matched non-pregnant women underwent whole-night respiratory recordings (airflow, snoring, respiratory movements, body position, pulse oximetry). The women also answered a questionnaire including the Epworth sleepiness scale.
Eighty-nine percent of the pregnant women had normal body mass index (BMI). Objectively, recorded snoring was more common among the pregnant women (median 9 % of total estimated sleep time) than among the controls (4 % of total sleep time, p = 0.005). Three of the pregnant women had OSA (apnea/hypopnea index (AHI) >5), but in two cases, this was mainly due to central hypopneas. None had AHI >10. Two controls were diagnosed as OSA. Respiratory parameters including snoring showed no impact on obstetric outcomes. Total Epworth sleepiness scale (ESS) score was higher among pregnant women than among controls (median 9 vs 7, p < 0.001). There was no difference concerning the separate items. There were no significant associations between either subjectively reported or objectively recorded snoring and ESS scores.
There was no increased prevalence of obstructive sleep apnea among pregnant women. One reason for this could be that the majority of the women in this study were non-obese. Neither OSA nor snoring was likely an explanation for the increased daytime sleepiness seen in the pregnant women.
KeywordsPregnancy Snoring Sleep recordings Sleep-disordered breathing Obstructive sleep apnea Epworth sleepiness scale
The authors thank Lena Harder, M.D., for initial scoring of the recordings of the pregnant women. We also thank research midwives Pia Cederholm and Cecilia Rostedt at the antenatal care center for valuable help with recruiting the women and collecting data.
Compliance with ethical standards
No funding was received for this research.
Conflict of interest
The authors declare that they have no competing interests.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 15.Iber C, American Academy of Sleep Medicine (2007) The AASM manual for the scoring of sleep and associated events: rules, terminology, and technical specifications. American Academy of Sleep Medicine. Westchester, ILGoogle Scholar
- 30.Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, Hudgel D, Sateia M, Schwab R, Portable Monitoring Task Force of the American Academy of Sleep M (2007) Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med 3(7):737–747PubMedGoogle Scholar
- 33.Arnardottir ES, Isleifsson B, Agustsson JS, Sigurdsson GA, Sigurgunnarsdottir MO, Sigurdarson GT, Saevarsson G, Sveinbjarnarson AT, Hoskuldsson S, Gislason T (2015) How to measure snoring? A comparison of the microphone, cannula and piezoelectric sensor. Journal of sleep research. doi: 10.1111/jsr.12356 Google Scholar
- 36.Moore KL, Dalley AF (2009) Clinically oriented anatomy, 6 edn. Williams and Wilkins, BaltimoreGoogle Scholar
- 37.Signal TL, Paine SJ, Sweeney B, Priston M, Muller D, Smith A, Lee KA, Huthwaite M, Reid P, Gander P (2014) Prevalence of abnormal sleep duration and excessive daytime sleepiness in pregnancy and the role of socio-demographic factors: comparing pregnant women with women in the general population. Sleep Med 15(12):1477–1483. doi: 10.1016/j.sleep.2014.07.007 CrossRefPubMedGoogle Scholar