Sleep and Breathing

, Volume 20, Issue 4, pp 1203–1208 | Cite as

Obstructive sleep apnea and urological comorbidities in males: a population-based study

  • Shiu-Dong Chung
  • Shih-Han Hung
  • Herng-Ching Lin
  • Ming-Chieh Tsai
  • Li-Ting Kao
Sleep Breathing Physiology and Disorders • Original Article



This study aimed to investigate associations between obstructive sleep apnea (OSA) and urological comorbidities using a large population-based dataset.


This cross-sectional study used the Taiwan Longitudinal Health Insurance Database 2005. We included 1236 males with OSA in the study group and 4944 males without OSA in the comparison group. Conditional logistic regressions were performed to examine relationships between OSA and urological comorbidities.


We found that patients with OSA had significantly greater prevalences of hypertrophy of the prostate (15.13 vs. 7.28 %), chronic prostatitis (4.37 vs. 2.16 %,), urinary incontinence (3.32 vs. 0.87 %), nocturia (2.02 vs. 0.61 %), erectile dysfunction (2.91 vs. 0.97 %), urinary calculi (12.06 vs. 6.80 %), and prostate cancer (0.97 vs. 0.40 %) than the comparison group. Additionally, the adjusted odds ratios in males with OSA for hypertrophy of prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer were 2.54 (95 % confidence interval (CI) 2.05~3.15), 1.95 (95 % CI 1.38~2.74), 4.13 (95 % CI 2.63~6.50), 3.54 (95 % CI 2.03~6.18), 2.95 (95 % CI 1.89~4.61), 1.89 (95 % CI 1.53~2.33), and 2.14 (95 % CI 1.03~4.43) than those without OSA, respectively.


This study concluded that males with OSA had higher odds ratios of hypertrophy of the prostate, chronic prostatitis, urinary incontinence, nocturia, erectile dysfunction, urinary calculi, and prostate cancer than comparison group.


Obstructive sleep apnea Urology Comorbidity Prostatitis Prostate 


Compliance with ethical standards

This study was exempted from full review by the institutional review board (IRB) after consulting with the director of National Defense Medical Center’s IRB, since the LHID2005 consists of de-identified secondary data released to the public for research purposes.

Competing interest

None declared.


No funding was received for this research.

Informed consent



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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Shiu-Dong Chung
    • 1
    • 2
    • 3
  • Shih-Han Hung
    • 4
  • Herng-Ching Lin
    • 3
    • 5
  • Ming-Chieh Tsai
    • 3
    • 6
  • Li-Ting Kao
    • 3
    • 7
  1. 1.Division of Urology, Department of SurgeryFar Eastern Memorial HospitalTaipeiTaiwan
  2. 2.Graduate Program in Biomedical Informatics, College of InformaticsYuan Ze UniversityChung-LiTaiwan
  3. 3.Sleep Research CenterTaipei Medical University HospitalTaipeiTaiwan
  4. 4.Department of OtolaryngologyTaipei Medical University HospitalTaipeiTaiwan
  5. 5.School of Health Care Administration, College of MedicineTaipei Medical UniversityTaipeiTaiwan
  6. 6.Department of Internal MedicineCathay General HospitalHsinchu BranchTaiwan
  7. 7.Graduate Institute of Life ScienceNational Defense Medical CenterTaipeiTaiwan

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