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Obstructive sleep apnea among hospitalized patients in Spain, analysis of hospital discharge data 2008–2012

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Abstract

Background

The aim of this study is to describe clinical characteristics, diagnostic and therapeutic procedure (polysomnography and continuous positive airway pressure (CPAP)/bi-level positive airway pressure (BPAP)), comorbidity, length of hospital stay (LOHS), discharge destination, and in-hospital mortality (IHM) of patients hospitalized for obstructive sleep apnea (OSA) in Spain over a 5-year study period.

Methods

We included all patients who were hospitalized for OSA (ICD9-CM code 327.23) as primary or secondary diagnosis between 2008 and 2012. Data were collected from the National Hospital Discharge Database, covering the entire Spanish population.

Results

We identified 196,769 discharges of patients admitted for OSA. The number of patients with OSA as primary or secondary diagnosis increased from 2008 to 2012 from 5358 to 7992 and 14,916 to 51,135 respectively. The mean age was 50.7 ± 20.3 years in patients admitted for OSA as primary diagnosis (n = 32,010) and 63.7 ± 17.6 years in patients admitted for OSA as secondary diagnosis (n = 164,759). The most common secondary diagnoses for patients discharged with a primary diagnosis of OSA was arterial hypertension (19.0 %), obesity (16.9 %), disorders of lipid metabolism (8.01 %) and diabetes mellitus (6.48 %). The most common primary diagnoses for patients discharged with a secondary diagnosis of OSA were obesity (12.5 %), heart failure (9.6 %), and chronic bronchitis (4.5 %). The percentage of patients that received continuous positive airway pressure (CPAP)/bi-level positive airway pressure (BPAP) therapy was 11.3 %. Patients who received this therapy had a higher length of stay compared with those who did not (10.4 ± 14.1 versus 7.3 ± 9.5 days, respectively, p < 0.05) and were less likely to be discharged to home (87.2 versus 91.1 %, p < 0.05). The mortality was higher in the first group of patients (9 versus 5.6 %, p < 0.05). Multivariate analysis showed that each year from 2008 to 2012, the mean probability of having OSA as primary diagnosis increased an average of 8 %, and 33 % as secondary diagnosis, after adjusting for other variables.

Conclusions

The results of this study reveal a national perspective on the characteristics and management of OSA in hospitalized patients in Spain during the period of 2008–2012. The burden of the disease seems to be increasing in Spain. Clinical studies are needed to provide a better knowledge of OSA in this subgroup of patients.

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Conflict of interests

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Pneumology Department, Hospital General Universitario Gregorio Marañon, C/ Doctor Esquerdo 46, 28007, Madrid, Spain

    Javier de Miguel-Díez & Luis Puente-Maestu

  2. Preventive Medicine and Public Health Teaching and Research Unit, Department of Health Sciences, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain

    Pilar Carrasco-Garrido, Rodrigo Jiménez-García, Valentín Hernández-Barrera & Ana López de Andrés

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  1. Javier de Miguel-Díez
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  2. Pilar Carrasco-Garrido
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  3. Rodrigo Jiménez-García
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  4. Luis Puente-Maestu
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  5. Valentín Hernández-Barrera
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  6. Ana López de Andrés
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Correspondence to Javier de Miguel-Díez.

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de Miguel-Díez, J., Carrasco-Garrido, P., Jiménez-García, R. et al. Obstructive sleep apnea among hospitalized patients in Spain, analysis of hospital discharge data 2008–2012. Sleep Breath 19, 841–848 (2015). https://doi.org/10.1007/s11325-014-1104-8

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  • DOI: https://doi.org/10.1007/s11325-014-1104-8

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