Sleep and Breathing

, Volume 11, Issue 4, pp 305–307 | Cite as

Adult obstructive sleep apnea related to nasopharyngeal obstruction: a case of retropharyngeal lipoma and pathogenetic considerations

  • Ottavio PiccinEmail author
  • Giovanni Sorrenti
Case Report


Cervico facial lipomas are relatively rare and only a few of them affect retropharyngeal space. Because of their slow growth rate, they can reach large size before causing respiratory disturbances and surgery is the treatment of choice. We present a case of 73-year-old female patient with severe obstructive sleep apnea [Apnea Hypopnea Index (AHI) = 43; mean SaO2 = 84%; lowest SaO2 = 60%; time of sleep with SaO2<90% = 35%]. Computed tomography scan showed a low attenuation bilobed retropharyngeal mass (5 × 2 × 2.5 cm) compatible with lipoma, extending from the nasopharynx to the superior bound of the oropharynx (at the level of C2–C3 passage). Removal of the tumor cured the obstructive sleep apnea; the sleep study at 1 month follow-up showed the normalization of the somnographic parameters (AHI = 12; lowest SaO2 = 76%; mean SaO2 = 95%; time of sleep with SaO2<90% = 4%).


Obstructive sleep apnea Nasopharyngeal obstruction Retropharyngeal lipoma 


  1. 1.
    Yoshihara H, Kawano K, Mita N (1998) Retropharyngeal lipoma causing severe dysphagia and dyspnea. J Otolaryngol 27:363–366PubMedGoogle Scholar
  2. 2.
    Aland GW Jr. (1996) Retropharyngeal lipoma causing symptoms of obstructive sleep apnea. Otolaryngol Head Neck Surg 114:628–630PubMedCrossRefGoogle Scholar
  3. 3.
    Di Girolamo S, Marinelli L, Galli A et al (1998) Retropharyngeal lipoma causing sleep apnea syndrome. Oral Maxillofac Surg 56:1003–1004CrossRefGoogle Scholar
  4. 4.
    Hockstein NG, Anderson TA, Moonis G et al (2002) Retropharyngeal lipoma causing obstructive sleep apnea: case report including five years follow-up. Laryngoscope 112:1603–1605PubMedCrossRefGoogle Scholar
  5. 5.
    Sher AE (1990) Obstructive sleep apnea syndrome: a complex disorder of the upper airway. Otolaryngol Clin North Am 23:593–608PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.ENT Department, S. Orsola HospitalBologna UniversityBolognaItaly

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