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Inspired Oxygen Concentrations during Positive Pressure Therapy

Sleep and Breathing volume 8, pages 1–5 (2004)Cite this article

Abstract

Objectives: This study examined the effects of various factors that might influence the fraction of oxygen in inspired air (FiO2) in a human and in a model system during nasal positive pressure treatments. Design and Methods: A healthy male volunteer and a mannequin head were each outfitted with a nasal continuous positive air pressure mask and pressure source (BiPAP S, Respironics, Murrysville, PA). Oxygen was added through either a side port in the mask or a port near the machine. Flow and FiO2were measured while varying inspiratory and expiratory pressures. Measurements were repeated with a leak added to the system and using different sites of oxygen administration. Results: In both the human and in the model system, increasing inspiratory pressure, thereby increasing flow, decreased FiO2inside the mask. In the model system, addition of a fixed leak caused an increase in flow and decrease in FiO2at any given level of inspiratory and expiratory pressure. Conclusion: In patients using nasal positive pressure therapy, variables of pressure, leak around the mask, and the site of oxygen delivery determine the inspired oxygen concentration when giving oxygen supplementation.

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Author information

Affiliations

  1. Louis Stokes Cleveland DVA Medical Center, Medical Service, Center for Sleep Disorders Research, Case Western Reserve University, Cleveland, Ohio

    Elizabeth A. Yoder M.D., Kenneth Klann & Kingman P. Strohl M.D.

  2. Internal Medicine Residency Program, University Hospitals of Cleveland, 11100 Euclid Ave., Cleveland, OH, 44106

    Elizabeth A. Yoder M.D.

Authors
  1. Elizabeth A. Yoder M.D.
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  2. Kenneth Klann
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  3. Kingman P. Strohl M.D.
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Corresponding author

Correspondence to Elizabeth A. Yoder M.D..

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Yoder, E.A., Klann, K. & Strohl, K.P. Inspired Oxygen Concentrations during Positive Pressure Therapy. Sleep Breath 8, 1–5 (2004). https://doi.org/10.1007/s11325-004-0001-y

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  • DOI: https://doi.org/10.1007/s11325-004-0001-y

Keywords

  • Sleep apnea
  • treatment
  • CPAP
  • oxygen