Abstract
Objectives: To evaluate subjective discomfort and somnographic measures of patients with obstructive sleep apnea and snoring problems who had been treated for 2 years with a mandibular protruding device (MPD). Methods: The study population comprised 65 patients with a pretreatment diagnosis of obstructive sleep apnea (OSA) (n = 44) or habitual snoring without apnea (n = 21). After a baseline medical and somnographic examination, a functional examination of the stomatognathic system, and a questionnaire focused on sleep-related qualities, each patient received an MPD. Two follow-ups were made 6 months and 2 years after MPD treatment had been initiated, and all initial examinations were repeated. Results: At the 2-year follow-up, significant subjective improvements were registered in 90% of the patients regarding a reduction of snoring and apneas, in 76% regarding a reduction in daytime tiredness, and in 84% regarding an improvement in the quality of the night sleep (change of ≥ 50% from baseline data). At the 2-year follow-up of the OSA group, the oxygen desaturation index (ODI) had dropped significantly from a mean value of 14.7 (SD, 12.7) to 3.1 (SD, 4.2) (P < 0.001), and the mean SaO2 nadir rose from 78.2% (SD, 8.1) to 89.0% (SD, 4.7) (P < 0.001). Only one of the snorers increased his ODI value; the others retained their initial healthy values. The OSA patients significantly reduced the amount of time they snored during their sleep. Conclusion: MPD treatment is associated with a significant reduction in subjective complaints such as disturbing snoring, apneas, daytime tiredness, and poor quality of night sleep, and with a significant reduction in ODI values in the OSA group. In addition, favorable 6-month results were unchanged after 2 years.
This is a preview of subscription content, access via your institution.
References
Svanborg E. Upper airway nerve lesions in obstructive sleep apnea. Am J Respir Crit Care Med 2001;164:187–189
Schmidt-Nowara W. A review of sleep disorders. The history and diagnosis of sleep disorders related to the dentist. Dent Clin North Am 2001;45:631–642
Lindberg E. Snoring and sleep apnea. A study of evolution and consequences in a male population. Minireview based on a doctoral thesis. Ups J Med Sci 1998;103:155–202
Partinen M, Jamieson A, Guilleminault C. Long-term outcome for obstructive sleep apnea patients. Mortality. Chest 1988;94:1200–1204
Marklund M, Franklin KA, SahlinC, Lundgren R. The effect of a mandibular advancement device on apneas and sleep in patients with obstructive sleep apnea. Chest 1998;113:707–713
Clark GT, Arand D, Chung E, Tong D. Effect of anterior mandibular positioning on obstructive sleep apnea. Am Rev Respir Dis 1993;147:624–629
O’Sullivan R, Hillman D, Mateljan R, Pantin C, Finucane K. Mandibular advancement splint: an appliance to treat snoring and obstructive sleep apnea. Am J Respir Crit Care Med 1995;151:194–198
Menn SJ, Loube DI, Morgan TD, Mitler MM, Berger JS, Erman MK. The mandibular repositioning device: role in the treatment of obstructive sleep apnea. Sleep 1996;19:794–800
Marklund M, Persson M, FranklinKA. Treatment success with a mandibular advancement device is related to supine-dependent sleep apnea. Chest 1998;114:1630–1635
Cohen R. Obstructive sleep apnea: oral appliance therapy and severity of condition. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:388–392
Fransson AMC, Isacsson G, LeissnerLC, Näsman AB, Alton MK. Treatment of snoring and obstructive sleep apnea with a mandibular protruding device: an open-label study. Sleep Breath 2001;5:23–34
Fransson AMC, Svenson BAH, Isacsson G. The effect of posture and a mandibular protruding device on pharyngeal dimensions. A cephalometric study. Sleep Breath 2002;6:55–68
George PT. Treatment of snoring and obstructive sleep apnea with a dental device. Dent Update 1996;23:12–19
Fransson AMC, Tegelberg Å, Svenson BAH, Lennartsson B, Isacsson G. Influence of mandibular protruding device on airway passage and dentofacial characteristics in obstructive sleep apnea and snoring. Am J Orthod Dentofacial Orthop 2002;122:371–379
McGown AD, Makker HK, Battagel JM, L’Estrange PR, Grant HR, Spiro SG. Long-term use of mandibular advancement splints for snoring and obstructive sleep apnoea: a questionnaire survey. Eur Respir J 2001;17:462–466
Guilleminault C, Dement W. Sleep Apnea Syndromes. New York, NY: Alan R Liss; 1978.
Guilleminault C, Dement W. Sleeping and waking disorders: indications and techniques. Menlo Park, NJ: Addison-Wesley; 1982:155–212
Svanborg E, Carlsson-Nordlander B, Larsson H, Pirskanen R, Sterner J. Screening for sleep apnea syndrome: static charge sensitive bed and ear oxymetry. Electroencephalogr Clin Neurophysiol 1986;64:86P–86P
Leissner LC, Leissner P. SAS-screening enl Örebro, en effektiv undersökningsmetod. Annual general meeting of the Swedish Society of Medicine November 25–27; 1992:268–268.
Hasan J, Alihanka J. Construction of REM-nREM sleep hypnograms from body movement recordings. Sleep 1980; 5th Eur Congr Sleep Res, Amsterdam; 1980:S344–S347
Svanborg E, Larsson H, Carlsson-Nordlander B, Pirskanen R. A limited diagnostic investigation for obstructive sleep apnea syndrome. Oximetry and static charge sensitive bed. Chest. 1990;98:1341–1345.
Block A, Boysen P, Wynne J, Hunt L. Sleep apnea, hypopnea and oxygen desaturation in normal subjects. A strong male predominance. N Engl J Med 1979;300:513–517
Wynne J, Block A, Hemenway J, Hunt L, Flick M. Disordered breathing and oxygen desaturation during sleep in patients with chronic obstructive lung disease (COLD). Am J Med 1979;66:573–579
Wilhelmsson B, Tegelberg Å, Walker-Engström M-L, et al. A prospective randomized study of a dental appliance compared with uvulopalatopharyngoplasty in the treatment of obstructive sleep apnoea. Acta Otolaryngol 1999;119:503–509
Walker-Engström M-L, Tegelberg Å, Wilhelmsson B, Ringqvist I. 4-year follow-up of treatment with dental appliance or uvulopalatopharyngoplasty in patients with obstructive sleep apnea. Chest 2002;121:739–746
Svanborg E, Larsson H. Development of nocturnal respiratory disturbance in untreated patients with obstructive sleep apnea syndrome. Chest 1993;104:340–343
Marklund M, Sahlin C, Stenlund H, Persson M, Franklin K. Mandibular advancement device in patients with obstructive sleep apnea: long-term effects on apnea and sleep. Chest 2001;120:162–169
Yoshida K. Influence of sleep posture on response to oral appliance therapy for sleep apnea syndrome. Sleep 2001;24:538–544
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Fransson, A.M.C., Tegelberg, Å., Leissner, L. et al. Effects of a Mandibular Protruding Device on the Sleep of Patients with Obstructive Sleep Apnea and Snoring Problems: A 2-Year Follow-Up. Sleep Breath 7, 131–141 (2003). https://doi.org/10.1007/s11325-003-0131-7
Issue Date:
DOI: https://doi.org/10.1007/s11325-003-0131-7
Keywords
- Sleep apnea
- snoring
- mandibular protruding device
- sleep quality questionnaire