Sleep and Breathing

, Volume 7, Issue 3, pp 131–141 | Cite as

Effects of a Mandibular Protruding Device on the Sleep of Patients with Obstructive Sleep Apnea and Snoring Problems: A 2-Year Follow-Up

  • Anette M. C. Fransson
  • Åke Tegelberg
  • Lena Leissner
  • Bengt Wenneberg
  • Göran Isacsson
Original Article


Objectives: To evaluate subjective discomfort and somnographic measures of patients with obstructive sleep apnea and snoring problems who had been treated for 2 years with a mandibular protruding device (MPD). Methods: The study population comprised 65 patients with a pretreatment diagnosis of obstructive sleep apnea (OSA) (n = 44) or habitual snoring without apnea (n = 21). After a baseline medical and somnographic examination, a functional examination of the stomatognathic system, and a questionnaire focused on sleep-related qualities, each patient received an MPD. Two follow-ups were made 6 months and 2 years after MPD treatment had been initiated, and all initial examinations were repeated. Results: At the 2-year follow-up, significant subjective improvements were registered in 90% of the patients regarding a reduction of snoring and apneas, in 76% regarding a reduction in daytime tiredness, and in 84% regarding an improvement in the quality of the night sleep (change of ≥ 50% from baseline data). At the 2-year follow-up of the OSA group, the oxygen desaturation index (ODI) had dropped significantly from a mean value of 14.7 (SD, 12.7) to 3.1 (SD, 4.2) (P < 0.001), and the mean SaO2 nadir rose from 78.2% (SD, 8.1) to 89.0% (SD, 4.7) (P < 0.001). Only one of the snorers increased his ODI value; the others retained their initial healthy values. The OSA patients significantly reduced the amount of time they snored during their sleep. Conclusion: MPD treatment is associated with a significant reduction in subjective complaints such as disturbing snoring, apneas, daytime tiredness, and poor quality of night sleep, and with a significant reduction in ODI values in the OSA group. In addition, favorable 6-month results were unchanged after 2 years.


Sleep apnea snoring mandibular protruding device sleep quality questionnaire 


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Copyright information

© Thieme Medical Publishers, Inc. 2003

Authors and Affiliations

  • Anette M. C. Fransson
    • 1
    • 4
    • 5
  • Åke Tegelberg
    • 2
  • Lena Leissner
    • 3
  • Bengt Wenneberg
    • 4
  • Göran Isacsson
    • 5
  1. 1.Department of Orthodontics and Department of Stomatognathic PhysiologyPostgraduate Dental Education CenterÖrebroSweden
  2. 2.Department of Stomatognathic Physiology and Centre for Clinical ResearchUppsala University, Central HospitalVästeråSweden
  3. 3.Sleep Unit, Department of NeurologyÖrebro University HospitalÖrebroSweden
  4. 4.Department of Stomatognathic Physiology, Faculty of OdontologyThe Sahlgrenska Academy, Göteborg UniversityGöteborgSweden
  5. 5.AstraZenecaSödertäljeSweden

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