Molecular Imaging and Biology

, Volume 19, Issue 3, pp 385–390 | Cite as

Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging

  • Bo Zheng
  • Elaine Yu
  • Ryan Orendorff
  • Kuan Lu
  • Justin J Konkle
  • Zhi Wei Tay
  • Daniel Hensley
  • Xinyi Y Zhou
  • Prashant Chandrasekharan
  • Emine U Saritas
  • Patrick W Goodwill
  • John D Hazle
  • Steven M Conolly
Special Topic


Magnetic particle imaging (MPI) is a new molecular imaging technique that directly images superparamagnetic tracers with high image contrast and sensitivity approaching nuclear medicine techniques—but without ionizing radiation. Since its inception, the MPI research field has quickly progressed in imaging theory, hardware, tracer design, and biomedical applications. Here, we describe the history and field of MPI, outline pressing challenges to MPI technology and clinical translation, highlight unique applications in MPI, and describe the role of the WMIS MPI Interest Group in collaboratively advancing MPI as a molecular imaging technique. We invite interested investigators to join the MPI Interest Group and contribute new insights and innovations to the MPI field.

Key words

Magnetic particle imaging Superparamagnetic iron oxide Interest group 



We are grateful for funding support from the Keck Foundation Grant 009323, NIH 1R01EB019458, NIH 1R24MH106053, and a UC Discovery Grant.

Compliance with Ethical Standards

Conflict of Interest

PWG and SMC are founders of Magnetic Insight. PWG, DWH, and JJK are employees of Magnetic Insight.


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Copyright information

© World Molecular Imaging Society 2017

Authors and Affiliations

  • Bo Zheng
    • 1
  • Elaine Yu
    • 1
  • Ryan Orendorff
    • 1
  • Kuan Lu
    • 2
  • Justin J Konkle
    • 3
  • Zhi Wei Tay
    • 1
  • Daniel Hensley
    • 1
    • 3
  • Xinyi Y Zhou
    • 1
  • Prashant Chandrasekharan
    • 1
  • Emine U Saritas
    • 4
    • 5
  • Patrick W Goodwill
    • 3
  • John D Hazle
    • 6
  • Steven M Conolly
    • 1
    • 7
  1. 1.Department of BioengineeringUC BerkeleyBerkeleyUSA
  2. 2.Triple Ring TechnologiesNewarkUSA
  3. 3.Magnetic InsightAlamedaUSA
  4. 4.Department of Electrical and Electronics EngineeringBilkent UniversityAnkaraTurkey
  5. 5.National Magnetic Resonance Research Center (UMRAM)Bilkent UniversityAnkaraTurkey
  6. 6.Department of Imaging PhysicsThe University of Texas MD Anderson Cancer CenterHoustonUSA
  7. 7.Department of Electrical Engineering and Computer ScienceUC BerkeleyBerkeleyUSA

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