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Table 1 Reconstruction scope

From: Recon 2.2: from reconstruction to model of human metabolism

  Recon 2.2 Quek Recon 2.1 Recon 2.04 Recon 2 Recon 1
Metabolites 5324 4962 5056 5063 5063 2766
Reactions 7785 7327 8089 7440 7440 3742
 Balanced 7780 6761 7916 6948 6948 431
 Unbalanced 0 211 51 94 94  
 Unknown 5a 355 122 398 398 3311
Genes 1675b 2167 2193 2140 2191  
  1. Recon 2.2 has increased the number of metabolites and reactions catalogued in the reconstruction relative to Recon 2, and the reactions have now been verified and corrected for mass balance. Note that boundary metabolites are excluded from this table (boundary metabolites being those outside of the system). The values for metabolites and reactions therefore correspond to the size of the stoichiometry matrix
  2. aThe 5 unbalanced reactions remaining in Recon 2.2 are those relating to the biomass objective function
  3. bThere appears to be fewer genes in Recon 2.2 than in previous reconstructions, due to the movement to representing genes by HGNC identifiers, which group alternative transcripts or splice variants into a single entity