Skip to main content
Log in

P2Y14 receptors: a new target for treating ulcerative colitis

  • Journal Club
  • Published:
Purinergic Signalling Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Data availability

No datasets were generated or analyzed during the current study.

References

  1. Liu C, Wang H, Han L, Zhu Y, Ni S, Zhi J, Yang X, Zhi J, Sheng T, Li H, Hu Q (2024) Targeting P2Y14R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis. Nat Commun 15(1):2083. https://doi.org/10.1038/s41467-024-46365-x

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Le Berre C, Honap S, Peyrin-Biroulet L (2023) Ulcerative colitis. Lancet 402(10401):571–584. https://doi.org/10.1016/S0140-6736(23)00966-2

    Article  PubMed  Google Scholar 

  3. Al-Horani R, Spanudakis E, Hamad B (2022) The market for ulcerative colitis. Nat Rev Drug Discov 21(1):15–16. https://doi.org/10.1038/d41573-021-00194-5

    Article  CAS  PubMed  Google Scholar 

  4. Hirten RP, Sands BE (2021) New therapeutics for ulcerative colitis. Annu Rev Med 27(72):199–213. https://doi.org/10.1146/annurev-med-052919-120048

    Article  CAS  Google Scholar 

  5. AlAmeel T, AlMutairdi A, Al-Bawardy B (2023) Emerging therapies for ulcerative colitis: updates from recent clinical trials. Clin Exp Gastroenterol 17(16):147–167. https://doi.org/10.2147/CEG.S375969

    Article  Google Scholar 

Download references

Funding

The authors were supported from the Sichuan Provincial Administration of Traditional Chinese Medicine (2023zd024) and Sichuan Science and Technology Program (2022NSFSC0852).

Author information

Authors and Affiliations

Authors

Contributions

YQZ and YT wrote the main manuscript text, and all authors reviewed the manuscript.

Corresponding author

Correspondence to Yong Tang.

Ethics declarations

Competing interests

The authors declare no competing interests.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflicts of interest

Yan-Qin Zuo declares that he/she has no conflict of interest. Yong Tang declares that he/she has no conflict of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zuo, YQ., Tang, Y. P2Y14 receptors: a new target for treating ulcerative colitis. Purinergic Signalling (2024). https://doi.org/10.1007/s11302-024-10017-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11302-024-10017-y

Keywords

Navigation