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Diagnostic utility of magnetic resonance imaging texture analysis in suppurative osteomyelitis of the mandible

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Abstract

Purpose

This study aimed to determine the diagnostic utility of magnetic resonance imaging (MRI) texture analysis for evaluating mandibular suppurative osteomyelitis (OM).

Materials and methods

In this retrospective cohort study, we analyzed the records of 50 patients with and without OM who underwent MRI between April 2019 and March 2021. The presence or absence of OM served as a predictor variable. The outcome variables were the texture features of the region of interest, which were analyzed. Quantitative parameters based on histogram features (90th percentile) and gray-level co-occurrence matrix (GLCM) features (Sum Averg) were calculated using short-tau inversion-recovery data with a region of interest. These six features out of 279 parameters were selected using Fisher, probability of error, and average correlation coefficient methods in MaZda. For the analysis of trivariate statistics, the post-Mann–Whitney test of the Kruskal–Wallis test with Bonferroni adjustment was used, and the p value was set to 0.05. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic effect of texture function to distinguish between acute and chronic diseases.

Results

One histogram feature and five GLCM features showed differences among the non-OM patients, acute OM patients, and chronic OM patients (p < 0.05). The ROC analysis revealed a high area under the curve ranging from 0.91 to 0.96 for six texture features.

Conclusion

The six texture features of the mandibular bone marrow demonstrated differences among patients without and with acute and chronic OM. MRI texture analysis may facilitate accurate assessment of the mandibular OM stage.

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Abbreviations

OM:

Osteomyelitis

MRI:

Magnetic resonance imaging

DWI:

Diffusion-weighted imaging

CBCT:

Cone-beam computed tomography

STIR:

Short tau inversion recovery

GLCM:

Gray-level co-occurrence matrix

AUC:

Area under the curve

ROC:

Receiver operating characteristic

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Authors and Affiliations

  1. Department of Radiology, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba, 271-8587, Japan

    Hirotaka Muraoka, Takashi Kaneda, Kotaro Ito, Naohisa Hirahara, Shungo Ichiki & Takumi Kondo

Authors
  1. Hirotaka Muraoka
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  2. Takashi Kaneda
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  3. Kotaro Ito
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  4. Naohisa Hirahara
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  5. Shungo Ichiki
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  6. Takumi Kondo
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Corresponding author

Correspondence to Hirotaka Muraoka.

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The authors declare that they have no conflict of interest.

Ethics approval

We designed and conducted a retrospective cohort study, which was approved by Nihon University Ethics Committee (EC19-011).

Informed consent

The requirement to obtain written informed consent was waived for this retrospective study. All procedures followed the guidelines of the Declaration of Helsinki, Ethical Principles for Medical Research Involving Human Subjects.

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This article does not contain any studies with animal subjects performed by the any of the authors.

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Muraoka, H., Kaneda, T., Ito, K. et al. Diagnostic utility of magnetic resonance imaging texture analysis in suppurative osteomyelitis of the mandible. Oral Radiol 38, 601–609 (2022). https://doi.org/10.1007/s11282-022-00595-1

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  • DOI: https://doi.org/10.1007/s11282-022-00595-1

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