Application value of shear wave elastography in salivary gland tumors



The aims of this study were to retrospectively analyse the values of shear wave elastography (SWE) in differential diagnosis of salivary gland tumors (SGT).


A total of 56 patients with salivary gland lump(s) were examined by SWE for measuring and comparing the differences in various Young’s modules (malignant tumor (MT) and benign tumor (BT), parotid tumor (PA) and adenolymphomas (AL), etc.). All the cases were confirmed by surgery or fine needle aspiration pathology.


The 56 SGT cases included 10 cases MT, 27 cases of PA, 11 cases of AL, and 8 cases of other BT. There was no statistical significance in Young’s modules between group BT and group MT (both P > 0.05); the differences between group PA and group AL were statistically significant (P < 0.05), and the corresponding ROC curve analysis found that the diagnostic value of the maximum Young’s modulus was the highest with the best cut-off values and AUC as 32.4 KPa and 0.805. The sensitivity, specificity, and Yoden index of the diagnosis of PA and AL were 70.4%, 81.8%, and 0.522, respectively.


SWE can differentially diagnose PA and AL while not MT and BT in SGT.

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  1. 1.

    Reinheimer A, Vieira DS, Cordeiro MM, Rivero ER. Retrospective study of 124 cases of salivary gland tumors and literature review. J Clin Exp Dent. 2019;11:e1025–32.

    PubMed  PubMed Central  Google Scholar 

  2. 2.

    Pantanowitz L, Thompson LDR, Rossi ED. Diagnostic approach to fine needle aspirations of cystic lesions. Head Neck Pathol. 2018;12:548–61.

    Article  Google Scholar 

  3. 3.

    Mezei T, Mocan S, Ormenisan A, Baróti B, Iacob A. The value of fine needle aspiration cytology in the clinical management of rare salivary gland tumors. J Appl Oral Sci. 2018;26:e20170267.

    Article  Google Scholar 

  4. 4.

    Luciano N, Ferro F, Bombardieri S, Baldini C. Advances in salivary gland ultrasonography. Clin Exp Rheumatol. 2018;36(Suppl 114):159–64.

    PubMed  Google Scholar 

  5. 5.

    Berg WA, Mendelson EB, Cosgrove DO, Doré CJ, Gay J, Henry JP, et al. Quantitative maximum shear-wave stiffness of breast masses as a predictor of histopathologic severity. AJR Am J Roentgenol. 2015;205:448–55.

    Article  Google Scholar 

  6. 6.

    Chen M, Zhang KQ, Xu YF, Zhang SM, Cao Y, Sun WQ. Shear wave elastography and contrast-enhanced ultrasonography in the diagnosis of thyroid malignant nodules. Mol Clin Oncol. 2016;5:724–30.

    Article  Google Scholar 

  7. 7.

    Heřman J, Sedláčková Z, Vachutka J, Fürst T, Salzman R, Vomáčka J, et al. Differential diagnosis of parotid gland tumors: role of shear wave elastography. Biomed Res Int. 2017;2017:9234672.

    PubMed  PubMed Central  Google Scholar 

  8. 8.

    Badea I, Tamas-Szora A, Chiorean I, Crisan M, Ciuleanu E, Baciut G, et al. Acoustic Radiation Force Impulse quantitative elastography: a new noninvasive technique for the evaluation of parotid glands. A preliminary study in controls and in patients with irradiated nasopharyngeal carcinoma. Med Ultrason. 2015;17:308–14.

    Article  Google Scholar 

  9. 9.

    Zhou H, Zhou XL, Xu HX, He YP, Bo XW, Li XL, et al. Initial experience with ultrasound elastography for diagnosis of major salivary gland lesions. J Ultrasound Med. 2016;35:2597–606.

    Article  Google Scholar 

  10. 10.

    Mansour N, Bas M, Stock KF, Strassen U, Hofauer B, Knopf A. Multimodal ultrasonographic pathway of parotid gland lesions. Ultraschall Med. 2017;38:166–73.

    PubMed  PubMed Central  Google Scholar 

  11. 11.

    Lee DH, Yoon TM, Lee JK, Lim SC. Clinical analysis of parotid tumors in patients over 60-year-old: a retrospective study of 78 cases. Int J Gerontol. 2017;11:114–7.

    Article  Google Scholar 

  12. 12.

    Deveer M, Sahan M, Sivrioglu AK, Celik OI. Bilateal multifocal Warthin tumours. BMJ Case Rep. 2013;2013:bcr2013009336.

    PubMed  PubMed Central  Google Scholar 

  13. 13.

    Fischer T, Paschen CF, Slowinski T, Alkhameri A, Berl JC, Klingebiel R, et al. Differentiation of parotid gland tumors with contrast-enhanced ultrasound. Rofo. 2010;182:155–62.

    Article  Google Scholar 

  14. 14.

    Gritzmann N. Sonography of the salivary glands. AJR Am J Roentgenol. 1989;153:161–6.

    Article  Google Scholar 

  15. 15.

    Khalife A, Bakhshaee M, Davachi B, Mashhadi L, Khazaeni K. The diagnostic value of B-mode sonography in differentiation of malignant and benign tumors of the parotid gland. Iran J Otorhinolaryngol. 2016;28:305–12.

    PubMed  PubMed Central  Google Scholar 

  16. 16.

    Mansour N, Stock KF, Chaker A, Bas M, Knopf A. Evaluation of parotid gland lesions with standard ultrasound, color duplex sonography, sonoelastography, and acoustic radiation force impulse imaging—a pilot study. Ultraschall Med. 2012;33:283–8.

    Article  Google Scholar 

  17. 17.

    Zheng M, Plonowska KA, Strohl MP, Ryan WR. Surgeon-performed ultrasound for the assessment of parotid masses. Am J Otolaryngol. 2018;39:467–71.

    Article  Google Scholar 

  18. 18.

    Wierzbicka M, Kałużny J, Szczepanek-Parulska E, Stangierski A, Gurgul E, Kopeć T, et al. Is sonoelastography a helpful method for evaluation of parotid tumors? Eur Arch Otorhinolaryngol. 2013;270:2101–7.

    Article  Google Scholar 

  19. 19.

    Bhatia KS, Cho CC, Tong CS, Lee YY, Yuen EH, Ahuja AT. Shear wave elastography of focal salivary gland lesions: preliminary experience in a routine head and neck US clinic. Eur Radiol. 2012;22:957–65.

    Article  Google Scholar 

  20. 20.

    Yu J, Du Y, Lu Y, Zhang W, Zhang D, Wang G, et al. Application of DTI and ARFI imaging in differential diagnosis of parotid tumours. Dentomaxillofac Radiol. 2016;45:20160100.

    Article  Google Scholar 

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Correspondence to Liping Jiang.

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Wang, J., Jiang, L. Application value of shear wave elastography in salivary gland tumors. Oral Radiol (2021).

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  • Shear wave elastography
  • Salivary gland tumors