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Low-dose cone-beam computed tomography in simulated condylar erosion detection: a diagnostic accuracy study

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Abstract

Objectives

The purpose of the present study was to assess the diagnostic accuracy of low-dose cone-beam computed tomography (CBCT) in the detection of simulated mandibular condyle erosions.

Methods

102 simulated erosions were performed on the condyles of eight dry human mandibles. Each mandible was subjected to four CBCT scan protocols: high-definition (HD), normal definition (NORM), ultra-low-dose high-definition (ULD-HD), and ultra-low-dose normal definition (ULD-NORM). All scans were analyzed by two observers. The inter-observer and intra-observer agreement as well as the agreement with the gold standard were assessed. The sensitivity, specificity, positive-predictive value, negative-predictive value and accuracy of erosion detection were calculated.

Results

A substantial to almost perfect agreement with the gold standard was found regarding the HD protocol and substantial agreement in NORM and ULD-HD protocols; however, moderate agreement was found regarding the ULD-NORM protocol. The sensitivity, specificity and accuracy values were highest for the HD protocol followed by the NORM and ULD-HD which showed comparable results; while, the ULD-NORM protocol showed the least values.

Conclusions

The studied ULD-HD CBCT protocol can be recommended for the detection of mandibular condylar erosions due to the reduced radiation dose; however, ULD-NORM is not advocated for similar clinical use.

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Acknowledgements

The authors would like to thank Yasmeen Abulmaaty, MSc. of Oral and Maxillofacial Radiology, for her assistance in the sample preparation, randomization and blinding.

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Correspondence to Noha Saleh Abu-Taleb.

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Author Noha Saleh Abu-Taleb and Author Dina Mohamed ElBeshlawy declare that they have no conflict of interest.

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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5).

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Abu-Taleb, N.S., ElBeshlawy, D.M. Low-dose cone-beam computed tomography in simulated condylar erosion detection: a diagnostic accuracy study. Oral Radiol 37, 427–435 (2021). https://doi.org/10.1007/s11282-020-00474-7

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  • DOI: https://doi.org/10.1007/s11282-020-00474-7

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