Abstract
Objectives
To evaluate the distribution of supernumerary teeth (ST) and the characteristics of mesiodens.
Methods
Panoramic radiographs of 48,700 outpatients were used to assess the distribution of ST. A total of 142 cone beam computed tomography (CBCT) images were used to evaluate the characteristics of mesiodens.
Results
A total of 1.24% of individuals aged from 1 to 98 years were diagnosed with ST among 48,700 outpatients, and males had a higher percentage of ST than females (2.94:1); patients aged 6–12 years were the most frequently diagnosed. More females had ST impacted in bone than males. The percentages of patients with 1 and 2 ST were 0.949 and 0.290%, respectively. The most frequent location, crown direction, and morphology of mesiodens were palatal, inverted, and conical, respectively. The tooth lengths of mesiodens in males and of erupted mesiodens were longer than that those in females and of unerupted mesiodens, respectively. Inverted mesiodens had the shortest tooth length compared with vertical and horizontal mesiodens. These results were statistically significant.
Conclusions
The distribution of ST and mesiodens were both related to gender, and patients aged 6–12 years were the most frequently detected. The length of the mesiodens was associated with the growth direction and mesiodens eruption.
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References
Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, et al. Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development. 2011;138(18):4063–73.
Alberti G, Mondani PM, Parodi V. Eruption of supernumerary permanent teeth in a sample of urban primary school population in Genoa. Italy Eur J Paediatr Dent. 2006;7:89–92.
De Oliveira GC, Drummond SN, Jham BC, Abdo EN, Mesquita RA. A survey of 460 supernumerary teeth in Brazilian children and adolescents. Int J Paediatr Dent. 2008;18:98–106.
Kim YY, Hwang J, Kim HS, Kwon HJ, Kim S, Lee JH, et al. Genetic alterations in mesiodens as revealed by targeted next-generation sequencing and gene co-occurrence network analysis. Oral Dis. 2017;23:966–72.
Syriac G, Joseph E, Rupesh S, Philip J, Cherian SA, Mathew J. Prevalence, characteristics, and complications of supernumerary teeth in nonsyndromic pediatric population of south India: a clinical and radiographic study. J Pharm Bioallied Sci. 2017;9:S231–S236236.
Herath C, Jayawardena C, Nagarathne N, Perera K. Characteristics and sequelae of erupted supernumerary teeth: a study of 218 cases among Sri Lankan children. J Investig Clin Dent. 2017;8:e12250.
Gomes RR, Fonseca JAC, Paula LM, Acevedo AC, Mestrinho HD. Dental anomalies in primary dentition and their corresponding permanent teeth. Clin Oral Investig. 2004;18:1361–7.
Nieminen P, Morgan NV, Fenwick AL, Parmanen S, Veistinen L, Mikkola ML, et al. Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. Am J Hum Genet. 2011;89:67–81.
Juuri E, Balic A. The biology underlying abnormalities of tooth number in humans. J Dent Res. 2017;96:1248–56.
Yu F, Cai W, Jiang B, Xu L, Liu S, Zhao S. A novel mutation of adenomatous polyposis coli (APC) gene results in the formation of supernumerary teeth. J Cell Mol Med. 2018;22:152–62.
Kriangkrai R, Chareonvit S, Yahagi K, Fujiwara M, Eto K, Iseki S. Study of Pax6 mutant rat revealed the association between upper incisor formation and midface formation. Dev Dyn. 2006;235:2134–43.
Tian Y, Ma P, Liu C, Yang X, Crawford DM, Yan W, et al. Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors. Eur J Oral Sci. 2015;123:396–402.
Munne PM, Tummers M, Jarvinen E, Thesleff I, Jernvall J. Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction. Development. 2009;136:393–402.
Colak H, Uzgur R, Tan E, Hamidi MM, Turkal M, Colak T. Investigation of prevalence and characteristics of mesiodens in a non-syndromic 11256 dental outpatients. Eur Rev Med Pharmacol Sci. 2013;17:2684–9.
Gallas MM, García A. Retention of permanent incisors by mesiodens: a family affair. Br Dent J. 2000;188(2):63–4.
Yun HJ, Jeong JS, Pang NS, Kwon IK, Jung BY. Radiographic assessment of clinical root-crown ratios of permanent teeth in a healthy Korean population. J Adv Prosthodont. 2014;6:171–6.
Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull. 1979;86(2):420–8.
Cicchetti DV. Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess. 1994;6(4):284–90.
Mossaz J, Kloukos D, Pandis N, Suter VG, Katsaros C, Bornstein MM. Morphologic characteristics, location, and associated complications of maxillary and mandibular supernumerary teeth as evaluated using cone beam computed tomography. Eur J Orthod. 2014;36:708–18.
Gurler G, Delilbasi C, Delilbasi E. Investigation of impacted supernumerary teeth: a cone beam computed tomograph (cbct) study. J Istanb Univ Fac Dent. 2017;51:18–24.
Lu X, Yu F, Liu J, Cai W, Zhao Y, Zhao S, et al. The epidemiology of supernumerary teeth and the associated molecular mechanism. Organogenesis. 2017;13:71–82.
Wang XP, Fan J. Molecular genetics of supernumerary tooth formation. Genesis. 2011;49:261–77.
McBeain M, Miloro M. Characteristics of supernumerary teeth in nonsyndromic population in an Urban dental school setting. J Oral Maxillofac Surg. 2017;76:933–8.
Singh VP, Sharma A, Sharma S. Supernumerary teeth in Nepalese children. Sci World J. 2014;2014:215396.
Yassin OM, Hamori E. Characteristics, clinical features and treatment of supernumerary teeth. J Clin Pediatr Dent. 2009;33:247–50.
Burhan AS, Nawaya FR, Arabi Katbi ME, Al-Jawabra AS. Prevalence of supernumerary teeth in a nonsyndromic Syrian sample. J Egypt Public Health Assoc. 2015;90:146–9.
Lagana G, Venza N, Borzabadi-Farahani A, Fabi F, Danesi C, Cozza P. Dental anomalies: prevalence and associations between them in a large sample of non-orthodontic subjects, a cross-sectional study. BMC Oral Health. 2017;17:62.
He D, Mei L, Wang Y, Li J, Li H. Association between maxillary anterior supernumerary teeth and impacted incisors in mixed dentition. J Am Dent Assoc. 2017;148:595–603.
Capitaneanu C, Willems G, Jacobs R, Fieuws S, Thevissen P. Sex estimation based on tooth measurements using panoramic radiographs. Int J Legal Med. 2017;131:813–21.
Koepke N, Floris J, Pfister C, Ruhli FJ, Staub K. Ladies first: female and male adult height in Switzerland, 1770–1930. Econ Human Biol. 2018;29:76–877.
Kim YH, Ahn KS, Cho KH, Kang CH, Cho SB, Han K, et al. Gender differences in the relationship between socioeconomic status and height loss among the elderly in South Korea: Korean National Health and Nutrition Examination Survey 2008–2010. Medicine. 2017;96:e7131.
Muhamad A, Moti M, Ornit C, Uri Z. Histological and chemical analyses of mesiodens development and mineralization. Arch Oral Biol. 2018;87:191–5.
Acknowledgements
We thank Dr. Fuyong Hu for his kind support in statistics. This study was funded by the Key Research and Development Projects of Department of Science and Technology of Anhui Province [Grant Number 1804h08020290].
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Lili Zhao, Shanshan Liu, Rongxiu Zhang, Ren Yang, Kai Zhang, and Xiaofei Xie declare that they have no conflict of interest.
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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent was obtained from all patients for being included in the study.
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Zhao, L., Liu, S., Zhang, R. et al. Analysis of the distribution of supernumerary teeth and the characteristics of mesiodens in Bengbu, China: a retrospective study. Oral Radiol 37, 218–223 (2021). https://doi.org/10.1007/s11282-020-00432-3
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DOI: https://doi.org/10.1007/s11282-020-00432-3