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Blockchain Framework for Collaborative Clinical Trials Auditing

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Abstract

Information management is Silos of the impending conditions across the sectors. Predominantly in the case of the clinical trials management, one of the critical challenges is about the information silos among the various stakeholder’s integral to the process. Processing the information over real-time and ensuring there is a holistic system in place shall help in improving the quality of collaboration and integration. The objective of this research article is to assess the feasibility of blockchain implementation for collaborative clinical trial auditing and to propose a blockchain-based solution that can help in improving the quality of solutions structure practised, leading to sustainable ways of handling the clinical trial auditing. The proposed model develops grid-based blocks for each of the phases of clinical trials, forming a comprehensive block network to be shared among the consortium handling the data. The proposed framework has a significant scope of security enhancement and customization that can help in shaping the systematic improvement to the information systems of clinical trials. The research methodology adopts the blockchain framework, which has been discussed in the paper. The consensus protocol used is Practical Byzantine Fault Tolerance (PBFT). The experimental study was conducted using simulation to verify the performance with regard to different performance metrics and attacks. The results showed that the proposed blockchain framework provides improved transaction throughput, reduced latency, and enhanced scalability, as compared to other existing models.

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Acknowledgements

I would like to express my sincere gratitude to Professor Zhaoshun Wang and to the School of Computer and Communication Engineering, University of Science and Technology, Beijing.

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  1. Department of Computer Science and Technology, School of Computer and Communication Engineering, University of Science and Technology Beijing (USTB), Beijing, 10083, China

    Nail Adeeb Ali Abdu & Zhaoshun Wang

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  1. Nail Adeeb Ali Abdu
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  2. Zhaoshun Wang
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Correspondence to Nail Adeeb Ali Abdu.

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Abdu, N.A.A., Wang, Z. Blockchain Framework for Collaborative Clinical Trials Auditing. Wireless Pers Commun 132, 39–65 (2023). https://doi.org/10.1007/s11277-023-10575-1

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