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Comparative analysis of flavonoids and polar metabolites from hairy roots of Scutellaria baicalensis and Scutellaria lateriflora

World Journal of Microbiology and Biotechnology volume 30, pages 887–892 (2014)Cite this article

Abstract

Baicalin, baicalein, and wogonin were accumulated in hairy roots derived from Scutellaria lateriflora and Scutellaria baicalensis. The levels of baicalein and baicalin were 6.8 and 5.0 times higher, respectively, in S. baicalensis than in S. lateriflora. A total of 47 metabolites were detected and identified in Scutellaria species by GC-TOF MS. The metabolites from the two species were subjected to principal component analysis (PCA) to evaluate differences. PCA fully distinguished between the two species. The results showed that individual phenolic acids and phenylalanine, precursors for the phenylpropanoid biosynthetic pathway, were higher in S. baicalensis than in S. lateriflora. This GC-TOF MS-based metabolic profiling approach was a viable alternative method to differentiate metabolic profiles between species.

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Acknowledgments

This work (K13101) was supported by the Korea Institute of Oriental Medicine (KIOM) grant funded by the Korea government and in part this study was supported by the National Academy of Agricultural Science (Code PJ0068342012), Rural Development Administration, Republic of Korea.

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Authors and Affiliations

  1. National Academy of Agricultural Science, Rural Development Administration, Suwon, 441-707, Korea

    Soo Yun Park

  2. KM-Based Herbal Drug Research Group Researcher, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon, 305-811, Korea

    Young Seon Kim & Mi Young Lee

  3. Department of Crop Science, College of Agriculture and Life Sciences, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea

    YeJi Kim, Md. Romij Uddin, Yeon Bok Kim & Sang Un Park

  4. Department of Well-Being Resources, Sunchon National University, 413 Jungangno, Suncheon, Jeollanam-do, 540-742, Korea

    Haeng Hoon Kim

  5. Department of Biosystems Machinery Engineering, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, Korea

    Sun Ok Chung

  6. Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 406-772, Korea

    Jae Kwang Kim

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  1. Jae Kwang Kim
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  8. Mi Young Lee
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  9. Sun Ok Chung
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Corresponding authors

Correspondence to Sun Ok Chung or Sang Un Park.

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Jae Kwang Kim and Young Seon Kim have contributed equally to this work.

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Kim, J.K., Kim, Y.S., Kim, Y. et al. Comparative analysis of flavonoids and polar metabolites from hairy roots of Scutellaria baicalensis and Scutellaria lateriflora . World J Microbiol Biotechnol 30, 887–892 (2014). https://doi.org/10.1007/s11274-013-1498-7

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  • DOI: https://doi.org/10.1007/s11274-013-1498-7

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