Abstract
The experimental data on the study of the antibacterial activity of purified phycocyanin, a protein-bound pigment isolated from blue-green alga, Spirulina platensis (Nordstedt) Geitler, Oscillatoriaceae are generalized and it was shown that phycocyanin was able to markedly inhibit the growth of drug resistant bacteria Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus while, no activity was recorded in Acinetobacter baumanii and Enterococcus durans, this is the first report of the activity of purified C-phycocyanin against drug resistant bacteria. The possible use of phycocyanin as a drug with associated antibacterial activity is discussed.
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Acknowledgments
The authors are thankful to former Director, CAS in Botany, University of Madras, for extending laboratory facilities and Prof. P. Reddanna, Hyderabad Central University, Hyderabad, for purification of phycocyanin.
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Sarada, D.V.L., Sreenath Kumar, C. & Rengasamy, R. Purified C-phycocyanin from Spirulina platensis (Nordstedt) Geitler: a novel and potent agent against drug resistant bacteria. World J Microbiol Biotechnol 27, 779–783 (2011). https://doi.org/10.1007/s11274-010-0516-2
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DOI: https://doi.org/10.1007/s11274-010-0516-2