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Spillover of Newcastle disease virus to Himalayan Griffon vulture: a possible food-based transmission

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Abstract

The Newcastle disease virus (NDV) affects wild and domesticated bird species, including commercial poultry. Although the diversity of NDV in domestic chickens is well documented, limited information is available about Newcastle disease (ND) outbreaks in other bird species. We report an annotated sequence of NDV/Vulture/Borjuri/01/22, an avirulent strain of NDV reported from Borjuri, Northeast India, in Himalayan Griffon vulture. The complete genome is 15,186 bases long with a fusion protein (F) cleavage site 112GRQGR↓L117. The phylogenetic analysis based on the F protein gene and the whole genome sequence revealed that the isolate from the vulture belongs to genotype II, sharing significant homology with vaccine strain LaSota. The study highlights the possible spillover of the virus from domestic to wild species through the food chain.

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Acknowledgements

The virus research in our laboratory is currently supported by the Department of Biotechnology, Government of India (BT/PR41246/NER/95/1685/2020) and Department of Health Research, Government of India (NER/71/2020-ECD-I).

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Authors and Affiliations

  1. Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India

    Shinjini Bhattacharya & Sachin Kumar

  2. Department of Microbiology, College of Veterinary Science, Assam Agricultural University Khanapara Campus, Guwahati, Assam, 781022, India

    Pankaj Deka & Sangeeta Das

  3. Centre for Wildlife Rehabilitation and Conservation, Kaziranga National Park, Bokakhat, Assam, 785612, India

    Samshul Ali

  4. Wildlife Trust of India, New Delhi, India

    Bhaskar Choudhury

  5. Life Science Education Trust, Bangalore, 560064, India

    Parikshit Kakati

Authors
  1. Shinjini Bhattacharya
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  7. Sachin Kumar
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Contributions

Shinjini Bhattacharya: Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing—original draft. Pankaj Deka: Conceptualization, Data curation, Formal analysis, Methodology. Sangeeta Das: Methodology, Samshul Ali: Methodology, Bhaskar Choudhury: Methodology, Parikshit Kakati: Methodology, Sachin Kumar: Conceptualization, Methodology, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing—review & editing.

Corresponding author

Correspondence to Sachin Kumar.

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The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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The study was conducted following the guidelines of the institutional biosafety committee (IBSC/2020/SEPT/SK/BSBE/6).

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Bhattacharya, S., Deka, P., Das, S. et al. Spillover of Newcastle disease virus to Himalayan Griffon vulture: a possible food-based transmission. Virus Genes (2024). https://doi.org/10.1007/s11262-024-02072-9

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