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H3K4me3 histone modification in baculovirus-infected silkworm cells

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Abstract

Baculovirus infection modulates the chromatin states and gene expression of host insect cells. Here we performed chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) of H3 trimethylated at Lys4 (H3K4me3) histone modification in Bombyx mori nucleopolyhedrovirus-infected Bombyx mori cells. The ChIP-seq data revealed the changes of the genome-wide distribution and accumulation of euchromatic histone marks in host insect cells during the progression of baculovirus infection.

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Fig. 1

Data availability

Deep sequencing data obtained in this study are available under the accession number DRA006274 (ChIP-seq) and DRA006275 (RNA-seq) (DDBJ).

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Acknowledgements

This work was supported by JSPS KAKENHI grant numbers 16H05051 and 19H02966 to S.K., and 16H06279 (PAGS) to Y.S.

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Author notes

  1. Keisuke Shoji, Ryuhei Kokusho and Susumu Katsuma have contributed equally to this work.

Authors and Affiliations

  1. Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan

    Keisuke Shoji

  2. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan

    Ryuhei Kokusho, Munetaka Kawamoto & Susumu Katsuma

  3. Division of Life Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan

    Ryuhei Kokusho

  4. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-0882, Japan

    Yutaka Suzuki

Authors
  1. Keisuke Shoji
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  2. Ryuhei Kokusho
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  3. Munetaka Kawamoto
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  4. Yutaka Suzuki
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  5. Susumu Katsuma
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Correspondence to Susumu Katsuma.

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The authors declared that they have no conflict of interest.

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Shoji, K., Kokusho, R., Kawamoto, M. et al. H3K4me3 histone modification in baculovirus-infected silkworm cells. Virus Genes 57, 459–463 (2021). https://doi.org/10.1007/s11262-021-01858-5

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  • DOI: https://doi.org/10.1007/s11262-021-01858-5

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