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First molecular detection of porcine circovirus type 3 in dogs in China

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Porcine circovirus type 3 (PCV3) has recently been isolated from diseased pigs within the USA. The objective was to detect the presence of PCV3 in dogs. Nested polymerase chain reactions (PCR) with PCV3-specific primers for the capsid gene were used to detect PCV3 genomic DNA in serum samples from dogs (n = 44) in China. There was PCV3 DNA detected in 4 of 44 dogs [all were negative for PCV2 and canine circovirus (CanineCV)]. Based on sequence analysis, positive sequences were grouped into PCV3 genotypes. However, these isolates had close evolutionary relationships with FoxCV (KP941114) and CanineCV (JQ821392). Further investigations of the epidemiology, evolutionary biology, and pathobiology of PCV3 to dogs are warranted.

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This project was supported by Research Foundation of Hunan Provincial Education Department, China (Grant No. 15A086); Postgraduate Research and Innovation Project of Hunan Province (Grant Nos. CX2016B285 and CX2016B314).

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NW, PJ and YY designed the research. JZ, ZL, YZ, NZ, DW, DT, LY and ZD helped with the experiments, data analysis, and discussion. JZ and NW wrote the manuscript.

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Correspondence to Ping Jiang or Naidong Wang.

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The authors declare that they have no conflict of interest regarding publication of this paper. All serum samples used in this study were collected as part of routine surveillance studies.

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Edited by Zhen F. Fu.

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Zhang, J., Liu, Z., Zou, Y. et al. First molecular detection of porcine circovirus type 3 in dogs in China. Virus Genes 54, 140–144 (2018).

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