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Alterations in coagulation parameters in dairy cows affected with acute mastitis caused by E. coli and S. aureus pathogens

Veterinary Research Communications volume 34, pages 533–539 (2010)Cite this article

Abstract

This study was conducted to evaluate alterations in coagulation parameters in dairy cows affected with acute Escherichia coli (E. coli) mastitis and to compare those values to cows affected with Staphylococcus aureus (S. aureus ) mastitis. Twenty-four, adult Holstein-Friesian dairy cows affected with acute E. coli mastitis and 17 cows affected with S. aureus mastitis were studied. Cows affected with E. coli mastitis had significantly prolonged activated partial thromboplastin time (APTT) (P < 0.01), prothrombin time (PT) (P < 0.05) and decreased (P < 0.05) platelets numbers. Cows with S. aureus mastitis had only significantly prolonged APTT (P < 0.05) and decreased (P < 0.05) platelet counts. In the hematology evaluation, cows affected with E. coli and those affected with S. aureus mastitis had elevated hematocrit values but only significantly (P < 0.05) so in mastitic cows caused by E. coli. Both groups of mastitic cows had significantly (P < 0.05) lower leukocyte counts. Only cows with E. coli mastitis had significantly (P < 0.05) lower neutrophil count. In the plasma biochemical evaluation, creatinine concentrations were significantly (P < 0.05) elevated in both groups of cows. Blood urea nitrogen (BUN) concentration was only significantly elevated in cows affected with E. coli mastitis. Results of this study indicated that dairy cows affected with acute E. coli mastitis are more likely to develop clinical manifestations of disseminated intravascular coagulation than cows affected with S. aureus mastitis.

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Abbreviations

E. coli :

Escherichia coli

S. aureus :

Staphylococcus aureus

BUN:

blood urea nitrogen

APTT:

activated partial thromboplastin time

PT:

prothrombin time

TT:

thrombin time

DIC:

disemminated intravascular coagulation

RBC:

red blood cell

TP:

total protein

Alb:

albumin

Mg:

magnesium

AST:

aspartate aminotransferase

GGT:

gamma glutamyl transferase

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Acknowledgements

The authors would like to thank Faculty and staff members of Schools of Veterinary Medicine at Jordan University of Science and Technology, Jordan and St. Mathews University, Cayman Islands for their support and enthusiasm.

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  1. Zuhair A. Bani Ismail

    Present address: Department of Veterinary Clinical Sciences, School of Veterinary Medicine, St. Matthews University, Grand Cayman Island, West Indies, KY1-1209, UK

Affiliations

  1. Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan

    Zuhair A. Bani Ismail

  2. Department of Veterinary Clinical Sciences, School of Veterinary Medicine, St. Matthews University, Grand Cayman Island, West Indies, KY1-1209, UK

    Charles Dickinson

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  1. Zuhair A. Bani Ismail
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Correspondence to Zuhair A. Bani Ismail.

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Bani Ismail, Z.A., Dickinson, C. Alterations in coagulation parameters in dairy cows affected with acute mastitis caused by E. coli and S. aureus pathogens. Vet Res Commun 34, 533–539 (2010). https://doi.org/10.1007/s11259-010-9424-z

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Keyword

  • Coagulation profiles
  • Dairy cow
  • Acute mastitis
  • Coagulopathy