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Vitamin E and Selenium Supplementation Reduces Plasma Cortisol and Oxidative Stress in Dystocia-Affected Buffaloes

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Abstract

The aim of the study was to evaluate oxidative stress around parturition in normally calved and dystocia-affected buffaloes and the clinical efficacy of vitamin E and selenium (Se) in reducing the effects in buffaloes suffering from dystocia. Plasma cortisol concentration, erythrocytic malondialdehyde (MDA) level and superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were evaluated in dystocia-affected (supplemented (n = 8) and unsupplemented (n = 5) with vitamin E and Se) and normally calved (unsupplemented; n = 6) buffaloes. The decline in plasma cortisol concentration, MDA level and SOD activity was greater in the group of dystocia-affected buffaloes supplemented with vitamin E and Se (78.62 ± 2.7%, 13.38 ± 9.75% and 28.83 ± 7.72%, respectively) than in the unsupplemented group (54.33 ± 12.62%, 3.48 ± 4.16% and 17.69 ± 12.93%, respectively). These results suggests that supplementation with antioxidants like vitamin E and Se may be beneficial in reducing oxidative stress in dystocia-affected buffaloes in the immediate postpartum period.

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Abbreviations

DCG:

dystocia control group

DTG:

dystocia treatment group

EG:

eutocia group

GADVASU:

Guru Angad Dev Veterinary and Animal Sciences University

GSH-Px:

glutathione peroxide

Hb:

haemoglobin

MDA:

malondialdehyde

ROM:

reactive oxygen metabolites

SEM:

standard error of mean

SOD:

superoxide dismutase

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Authors and Affiliations

  1. Department of Animal Reproduction, Gynaecology and Obstetrics, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India

    A. Sathya, S. Prabhakar & S. P. S. Ghuman

  2. Department of Veterinary Biochemistry, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India

    S. P. S. Sangha

Authors
  1. A. Sathya
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  2. S. Prabhakar
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  3. S. P. S. Sangha
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  4. S. P. S. Ghuman
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Correspondence to A. Sathya.

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Sathya, A., Prabhakar, S., Sangha, S.P.S. et al. Vitamin E and Selenium Supplementation Reduces Plasma Cortisol and Oxidative Stress in Dystocia-Affected Buffaloes. Vet Res Commun 31, 809–818 (2007). https://doi.org/10.1007/s11259-007-0116-2

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  • DOI: https://doi.org/10.1007/s11259-007-0116-2

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