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Effect of Mannheimia (Pasteurella) haemolytica Infection on Acute-phase Proteins and Some Mineral Levels in Colostrum–Breast Milk-fed or Colostrum–Breast Milk-deprived Sheep

Ulutas, P.A. and Ozpinar, A., 2006. Effect of Mannheimia (Pasteurella) haemolytica Infection on Acute-phase Proteins and Some Mineral Levels in Colostrum–Breast Milk-fed or Colostrum–Breast Milk-deprived Sheep.Veterinary Research Communications, 30(5), 485–495

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Abstract

The aim of this study was to investigate the levels of acute-phase proteins and minerals as indicators for the reactivity in 1-year-old sheep. A total of 26 Chios breed sheep were fed colostrum–breast milk (control, n = 15)or were deprived afterseparation from their mother immediately after birth(experimental, n = 11). Mannheimia (Pasteurella) haemolytica serotype A1 was inoculated intratracheally and blood samples were taken in vacuumed sera on days 0, 1, 4, 7, 10, 13, 16, 19 and 22. Antibiotic treatment was initiated after blood sampling on day 22, and blood samples were taken on days 1, 4 and 7 after the treatment. The levels of C-reactive protein (CRP), haptoglobin, ceruloplasmin, fibrinogen, zinc, iron and calcium, which are the indicators of immune function and infectious diseases were analysed. No significant difference between the control and trial groups before and after the infection was determined. However, serum CRP, haptoglobin, ceruloplasmin and fibrinogen levels were increased in the course of the infection. These levels were restored to normal following treatment.

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Abbreviations

APP:

acute-phase proteins

CRP:

C-reactive protein

IL:

interleukin

PMSG:

pregnant mare serum gonadotrophin

TNF:

tumor necrosis factor

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Authors and Affiliations

  1. Faculty of Veterinary Medicine, Department of Biochemistry, Adnan Menderes University, Isιklι, Aydιn

    P A Ulutas

  2. Faculty of Veterinary Medicine, Department of Biochemistry, Istanbul University, Istanbul, Turkey

    A Ozpinar

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  1. P A Ulutas
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  2. A Ozpinar
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Correspondence to P A Ulutas.

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Ulutas, P.A., Ozpinar, A. Effect of Mannheimia (Pasteurella) haemolytica Infection on Acute-phase Proteins and Some Mineral Levels in Colostrum–Breast Milk-fed or Colostrum–Breast Milk-deprived Sheep. Vet Res Commun 30, 485–495 (2006). https://doi.org/10.1007/s11259-006-3246-z

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