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Usefulness of the mayo adhesive probability score as a predictive factor for renal function deterioration after partial nephrectomy: a retrospective case–control study

  • Urology - Original Paper
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Abstract

Purpose

Whether the Mayo adhesive probability score, an index of the perinephric fat environment, could be a predictive factor for renal function deterioration after partial nephrectomy was investigated.

Methods

A retrospective case–control study of 78 patients who underwent laparoscopic partial nephrectomy was performed. An estimated glomerular filtration rate preservation rate at ≤ 90% at 3 months after surgery was defined as postoperative renal function deterioration. These patients were divided into two groups (non-deterioration and deterioration groups). Patient factors including Mayo adhesive probability scores (both tumor and unaffected sides) and surgical factors were evaluated to identify the predictors for postoperative renal function deterioration. The statistical analysis used univariate and multivariate logistic regression analyses.

Results

Thirty-seven (47.4%) patients had postoperative renal function deterioration after partial nephrectomy. Univariate analysis identified Mayo adhesive probability score on the unaffected side (p = 0.02), and warm ischemia time (p < 0.01) as predictors of postoperative renal function deterioration. On multivariate analyses, Mayo adhesive probability score on the unaffected side (odds ratio: 1.38 [1.05–1.79], p = 0.02) and warm ischemia time (odds ratio: 1.04 [1.01–1.07], p < 0.01) were significantly associated with postoperative renal function deterioration as same as univariate analysis. On receive operating characteristic curve analysis, Mayo adhesive probability score on the unaffected side (cutoff value 1.5; p = 0.02) and warm ischemia time (cutoff value 26.5 min; p = 0.01) were significant predictors of renal function deterioration 3 month after surgery.

Conclusion

The Mayo adhesive probability score on the unaffected side and warm ischemia time are useful predictors for renal function deterioration after partial nephrectomy.

Trial registration number

2019-249, January 21st, 2019, retrospectively registered.

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Availability of data and material

Data sharing is not applicable to this article as no datasets were generated or analysed during the current study.

Code availability

Not applicable.

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Funding

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Authors and Affiliations

  1. Department of Urology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295, Japan

    Junya Hata, Yuta Matsuoka, Akifumi Onagi, Ruriko Honda-Takinami, Kanako Matsuoka, Yuichi Sato, Hidenori Akaihata, Soichiro Ogawa, Masao Kataoka & Yoshiyuki Kojima

  2. Department of Urology, Takeda General Hospital, Aizuwakamatsu, Japan

    Takayuki Hosoi

Authors
  1. Junya Hata
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  2. Yuta Matsuoka
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  3. Akifumi Onagi
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  4. Ruriko Honda-Takinami
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  5. Kanako Matsuoka
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  6. Yuichi Sato
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  7. Hidenori Akaihata
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  8. Soichiro Ogawa
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  9. Masao Kataoka
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  10. Takayuki Hosoi
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  11. Yoshiyuki Kojima
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Contributions

HJ: project development and manuscript writing, MY, OA, HR: data collection. MK, SY, AH, OS, KM: data collection and data analysis, HT, KY: manuscript writing/editing. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Junya Hata.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethics approval

The present study’s retrospective protocol was performed in accordance with the Declaration of Helsinki and protocols approved by the ethics Committee of Fukushima Medical University (# 2019-249).

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Not applicable.

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Cite this article

Hata, J., Matsuoka, Y., Onagi, A. et al. Usefulness of the mayo adhesive probability score as a predictive factor for renal function deterioration after partial nephrectomy: a retrospective case–control study. Int Urol Nephrol 53, 2281–2288 (2021). https://doi.org/10.1007/s11255-021-02986-5

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  • DOI: https://doi.org/10.1007/s11255-021-02986-5

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