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Gender difference in the association of chronic kidney disease with visceral adiposity index and lipid accumulation product index in Korean adults: Korean National Health and Nutrition Examination Survey

International Urology and Nephrology volume 53, pages 1417–1425 (2021)Cite this article

Abstract

Background

This study was conducted to assess gender difference in the association of chronic kidney disease (CKD) with visceral adiposity index (VAI) and lipid accumulation product index (LAP) in Korean adults.

Materials and methods

The study was performed using data from the 2015 Korean National Health and Nutrition Examination Survey and included 4947 adults aged 20 years or older.

Results

There were several key findings in the present study. First, overall, after adjusting for related variables (including age), CKD (estimated glomerular filtration rate < 60 ml/min/1.73 m2) was positively associated with the quartiles of VAI and LAP. Second, when analyzed separately for gender, the results in men and women were different. After adjusting for the related variables (except age), CKD was positively associated with the quartiles of VAI and LAP in both men and women. After further adjustment for age, CKD was still positively associated with the quartiles of VAI and LAP in men. However, in women, the relationships between CKD and the quartiles of VAI and LAP were no longer significant.

Conclusions

The VAI and LAP index were positively associated with CKD in Korean men but not in women.

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Author information

Affiliations

  1. Department of Dental Hygiene, College of Health Science, Kangwon National University, 346, Hwangjo-gil, Dogye-eup, Samcheok-si, Gangwon-do, 25949, South Korea

    Jeong Min Seong

  2. Department of Clinical Laboratory Science, Wonkwang Health Science University, 514, Iksan-daero, Iksan, Jeollabuk-do, 54538, South Korea

    Jun Ho Lee & Hyun Yoon

  3. Department of Nursing, Christian College of Nursing, 6, Baekseoro 70 beongil, Namgu, Gwangju, 61662, South Korea

    Mi Young Gi

  4. Department of Sports Rehabilitation, Chosun College of Science and Technology, 309-1, Pilmun-daero, Dong-gu, Gwangju, 61453, South Korea

    Youn Hee Son

  5. Department of Dental Hygiene, Honam University, 417, Eodeung-daero, Gwangsan-gu, Gwangju, 62399, South Korea

    Ae Eun Moon

  6. Department of Biomedical Laboratory Science, Namseoul University, Cheonan-si, Chungcheongnam-do, 31020, South Korea

    Chang Eun Park

  7. Department of Clinical Laboratory Science, Dongnam Health University, 50, Cheoncheon-ro 74beon-gil, Jangan-gu, Suwon-si, Gyeonggi-do, 16328, South Korea

    Hyun Ho Sung

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  1. Jeong Min Seong
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Correspondence to Hyun Yoon.

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All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Declaration of Helsinki with its later amendments.

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Seong, J.M., Lee, J.H., Gi, M.Y. et al. Gender difference in the association of chronic kidney disease with visceral adiposity index and lipid accumulation product index in Korean adults: Korean National Health and Nutrition Examination Survey. Int Urol Nephrol 53, 1417–1425 (2021). https://doi.org/10.1007/s11255-020-02735-0

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  • DOI: https://doi.org/10.1007/s11255-020-02735-0

Keywords

  • Visceral adiposity index
  • Lipid accumulation product index
  • Chronic kidney disease
  • Gender difference