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Correlation between body composition measurement by bioelectrical impedance analysis and intradialytic hypotension

  • Nephrology - Original Paper
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Abstract

Objective

To explore the correlation between body composition measurement by bioelectrical impedance analysis (BIA) and intradialytic hypotension (IDH).

Methods

The clinical data of 127 patients with end-stage renal disease (ESRD) who underwent regular dialysis in the Blood Purification Center of the Second Affiliated Hospital of Chongqing Medical University were retrospectively analyzed. According to the occurrence of IDH, the patients were divided into IDH group and intradialytic normotension group. The difference in body composition measured by BIA and its relationship with IDH were compared between the two groups.

Results

Compared with intradialytic normotension group, the intracellular water (ICW) ratio (P = 0.009), extracellular water (ECW) ratio (P = 0.029), total body water (TBW) ratio (P = 0.012), protein ratio (P = 0.010), soft lean mass (SLM) ratio (P = 0.011), fat-free mass (FFM) ratio (P = 0.012) and skeletal muscle mass (SMM) ratio (P = 0.009) in IDH group were significantly decreased. However, the fat mass (FM) ratio (P = 0.016), percentage body fat (PBF) ratio (P = 0.001), extracellular water/total body water (ECW/TBW) ratio (P = 0.036), extracellular water/total body water in trunk (ECW/TBWT) ratio (P = 0.045) and visceral fat area (VFA) (P = 0.003) in IDH group were significantly increased when compared with intradialytic normotension group. In addition, there was a positive correlation between systolic blood pressure (SBP) during IDH and ECW ratio, ECW/TBW ratio, and ECW/TBWTR ratio before dialysis.

Conclusions

The body composition of dialysis patients is closely related to the occurrence of IDH. Strengthening the body composition management of dialysis patients outside the hospital may reduce the occurrence of IDH and improve the long-term prognosis of dialysis patients.

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Acknowledgements

We would like to thank all Fellows and Staff of the Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University.

Funding

This work was supported by China Postdoctoral Science Foundation funded project (no. 2018M633630XB), Science and Technology Research Program of Chongqing Municipal Education Commission (Grant no. KJQN201800403), the National Natural Science Foundation of China (Grant no. 81800771) and the Chongqing Science and Technology Commission (cstc2019jcyj-msxm0195).The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Author notes

  1. Qin Zhou and Jiaqi Wang contributed equally to this study.

Authors and Affiliations

  1. Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, Lingjiang Road, Yuzhong District, Chongqing, 400010, China

    Qin Zhou, Jiaqi Wang, Shuqin Xie, Shiyi Yuan, Ling Zhong & Jianwei Chen

Authors
  1. Qin Zhou
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  2. Jiaqi Wang
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  3. Shuqin Xie
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  4. Shiyi Yuan
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  5. Ling Zhong
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  6. Jianwei Chen
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Contributions

Conceived and designed the study: JW, and LZ. Performed the experimental procedures: JC, SY. Analyzed the data: SX, QZ. Drafted the manuscript: QZ, JW.

Corresponding authors

Correspondence to Ling Zhong or Jianwei Chen.

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Conflict of interest

The authors have no conflicts of interest to declare.

Statement of ethics

This study was approved by the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University (No. (2019) 250). All persons recruited for this study provided written informed consent prior to participation.

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Zhou, Q., Wang, J., Xie, S. et al. Correlation between body composition measurement by bioelectrical impedance analysis and intradialytic hypotension. Int Urol Nephrol 52, 953–958 (2020). https://doi.org/10.1007/s11255-020-02456-4

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  • DOI: https://doi.org/10.1007/s11255-020-02456-4

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