Evaluation of quality of life, physical, and mental aspects in longevous patients with chronic kidney disease
The diagnosis of chronic kidney disease (CKD) in elderly individuals has been increasing. The objective of this study was to evaluate physical, mental and social aspects in longevous elderly patients with CKD.
Eighty patients with CKD (stage 4 and 5, not on dialysis) and 60 longevous elderly (≥ 80 years) paired by gender and age living in the community were evaluated. Physical, cognitive, social and quality of life aspects were analyzed according to the following scales: Charlson comorbidity index, Medical Outcomes Study Short Form 36-Item (SF-36), Medical Outcomes Study, Boston Naming Test, verbal fluency test (animal naming), sit-to-stand test, gait speed, and the Mini-Mental state examination.
Compared to the control group, the CKD group had a higher mean in the comorbidities index (3.5 ± 1.2 vs. 1.0 ± 1, respectively, p < 0.001). In the multivariate analysis, the CKD group presented worse performance in the SF-36 dimensions: ‘physical functioning,’ ‘general health,’ ‘emotional functioning,’ ‘vitality,’ and physical component summary. On the other hand, they presented better results for the ‘mental health’ dimension, in addition to lower social support, worse verbal fluency and worse results on the sit-to-stand test.
Longevous patients with stage 4 or 5 CKD presented worse evaluation in several domains of physical and emotional functioning, lower social support and evidence of worse cognitive performance. These aspects should be taken into account in order to improve the care provided to these patients, improve their quality of life and prevent their morbidity.
KeywordsChronic kidney disease Dialysis Quality of life Physical evaluation Mental assessment
AM conceived the study, participated in acquisition of data, design of the study, performed statistical analysis, interpretation of data, preparation of manuscript, and read and approved the final manuscript. AA, OP participated in the design of the study, acquisition of data, interpretation of data, and read and approved the final manuscript; CG performed statistical analysis, interpretation of data, and read and approved the final manuscript; CA participated in data interpretation, manuscript preparation, and read and approved the final manuscript; MSC participated in acquisition of data, study design, data interpretation, and read and approved the final manuscript; RCS conceived the study, participated in the study design, performed statistical analysis, data interpretation, manuscript preparation, and read and approved the final manuscript.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
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