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Successful endovascular treatment of chronic renal artery occlusion: a preliminary retrospective case series including 15 patients

  • Nephrology - Original paper
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Abstract

Purpose

To evaluate in a retrospective, single-center, case series if percutaneous transluminal renal angioplasty/stenting of chronic renal artery occlusion is beneficial to renal function and blood pressure control, which remains controversial.

Methods

Data from 15 consecutive patients with renal artery stump who underwent successful percutaneous transluminal renal angioplasty/stenting only for unilateral chronic renal artery occlusion at our center from January 2007 to February 2018 and completed follow-up were retrospectively evaluated. Of the 15 patients, 14 (93.3%) were treated with stenting and 1 with only balloon angioplasty. Estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease (MDRD) formula corrected for Chinese, and changes in blood pressure and need for antihypertensive medications were recorded.

Results

At median 1.5-year (interquartile range 0.5–5.0) follow-up, restenosis rate was 20.0%. Renal function improved or remained stable in 26.7% and 53.3% of patients, respectively, and blood pressure normalized or improved in 13.3% and 40.0% of patients, respectively. Young patients with Takayasu’s arteritis or fibromuscular dysplasia appeared to benefit the most from revascularization.

Conclusions

In this preliminary retrospective series of select patients with renal artery stump, endovascular treatment of chronic renal artery occlusion appeared to preserve renal function and improve blood pressure.

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Acknowledgements

We thank Roberto Patarca for his linguistic assistance during the preparation of this manuscript.

Author information

Author notes

  1. Min Yang, Letao Lin and Guochen Niu contributed equally to this study and therefore share first authorship.

Authors and Affiliations

  1. Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, 8 Xishiku St, Beijing, 100034, People’s Republic of China

    Min Yang, Letao Lin, Guochen Niu, Ziguang Yan, Bihui Zhang, Xiaoqiang Tong & Yinghua Zou

Authors
  1. Min Yang
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  2. Letao Lin
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  3. Guochen Niu
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  4. Ziguang Yan
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  5. Bihui Zhang
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  6. Xiaoqiang Tong
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  7. Yinghua Zou
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Corresponding author

Correspondence to Yinghua Zou.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This retrospective study was approved by the Institutional Review Board with waiver of informed consent.

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Yang, M., Lin, L., Niu, G. et al. Successful endovascular treatment of chronic renal artery occlusion: a preliminary retrospective case series including 15 patients. Int Urol Nephrol 51, 285–291 (2019). https://doi.org/10.1007/s11255-018-02067-0

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  • DOI: https://doi.org/10.1007/s11255-018-02067-0

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