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A prospective, randomized trial to evaluate the efficacy of clean intermittent catheterization versus triamcinolone ointment and contractubex ointment of catheter following internal urethrotomy: long-term results

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Abstract

Purpose

Our aim was to evaluate clean intermittent catheterization (CIC) results in combination with triamcinolone ointment and contractubex ointment for lubrication of the catheter after optical internal urethrotomy (OIU).

Methods

Ninety patients who underwent OIU were randomized into three groups. Two weeks after operation, patients were treated with CIC (group A), triamcinolone ointment CIC (group B), and contractubex ointment CIC (group C). Follow-up continued for 24 months after the OIU. Postoperative results were compared between the three groups.

Results

There were no significant differences in the baseline characteristics of the patients or the etiology of the urethral stricture between the three groups. The mean preoperative Q max was 4.31 ml/s. The average score of preoperative international prostate symptom score (IPSS) was 23.1 points. In both groups, after treatment, significant improvements in Q max and IPSS were noted at all follow-up period (p < 0.05). But for Q max and IPSS, there were not any significant differences between groups at all follow-up period (p > 0.05). Overall recurrence rate was 28.9 % (26 out of 90 patients) at the end of the study. Recurrence rates were, however, not found to be statistically significant between these three groups (p > 0.05).

Conclusion

Our results indicate that the urethral dilation protocol with CIC after first OIU is a safe, simple, well-tolerated, office-based procedure. Triamcinolone or contractubex ointments of the CIC do not provide an additional benefit. Currently, urethral dilation with CIC after first OIU seems to be the only proven procedure that decreased the recurrence rate.

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Abbreviations

CIC:

Clean intermittent catheterization

OIU:

Optical internal urethrotomy

US:

Urethral stricture

IPSS:

International prostate symptom score

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Conflict of interest

The authors declare that they have no conflict of interests.

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Authors and Affiliations

  1. Department of Urology, KonyaTraining and Research Hospital, Konya, Turkey

    Osman Ergün

  2. Department of Urology, Aydın State Hospital, Aydın, Turkey

    Ahmet Güzel

  3. Department of Urology, Faculty of Medicine, Bezmialem Vakıf University, İstanbul, Turkey

    Abdullah Armağan

  4. Department of Urology, Medicalpark Hospital, Antalya, Turkey

    Alim Koşar

  5. Microbiology Laboratory, Konya Numune Hospital, Konya, Turkey

    Ayşe Gül Ergün

  6. Üroloji polikliniği, Konya Eğitim ve Araştırma Hastanesi, Hacı Şaban Mah., Meram Yeniyol Caddesi No: 97, Meram, Konya, PK, 42090, Turkey

    Osman Ergün

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  1. Osman Ergün
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  2. Ahmet Güzel
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  3. Abdullah Armağan
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  5. Ayşe Gül Ergün
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Correspondence to Osman Ergün.

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Ergün, O., Güzel, A., Armağan, A. et al. A prospective, randomized trial to evaluate the efficacy of clean intermittent catheterization versus triamcinolone ointment and contractubex ointment of catheter following internal urethrotomy: long-term results. Int Urol Nephrol 47, 909–913 (2015). https://doi.org/10.1007/s11255-015-0990-4

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  • DOI: https://doi.org/10.1007/s11255-015-0990-4

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