Abstract
Purpose
To compare the effectiveness of percutaneous tibial nerve stimulation (PTNS) using adhesive skin surface electrodes versus solifenacin succinate (SS) in patients with neurogenic detrusor overactivity (NDO) secondary to spinal cord injury (SCI).
Methods
A randomized controlled study involving 100 patients with NDO secondary to SCI was conducted. Patients were randomized into two groups. In group A, patients received PTNS using adhesive skin surface electrodes for 4 weeks. In group B, patients underwent SS treatment for 4 weeks. Bladder diaries and incontinence quality of life questionnaire were reviewed before treatment and 2 and 4 weeks after treatment.
Results
Improvement in all bladder diary parameters was statistically significant within each group 2 and 4 weeks after treatment compared to baseline (p < 0.05), but did not reach statistical significance between the PTNS and SS groups (p > 0.05). Compared to SS, PTNS was not associated with any unanticipated adverse events.
Conclusions
PTNS therapy with adhesive skin surface electrodes is an effective method to treat NDO secondary to SCI. This therapy is not only no difference comparing to SS therapy but also noninvasive and easily managed by patients.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Sahai A, Cortes E, Seth J et al (2011) Neurogenic detrusor overactivity in patients with spinal cord injury: evaluation and management. Curr Urol Rep 12:404–412
del Popolo G, Mencarini M, Nelli F et al (2012) Controversy over the pharmacological treatments of storage symptoms in spinal cord injury patients: a literature overview. Spinal Cord 50:8–13
Burton C, Sajja A, Latthe PM (2012) Effectiveness of percutaneous posterior tibial nerve stimulation for overactive bladder: a systematic review and meta-analysis. Neurourol Urodyn 31:1206–1216
Vecchioli-Scaldazza C, Morosetti C, Berouz A et al (2013) Solifenacin succinate versus percutaneous tibial nerve stimulation in women with overactive bladder syndrome: results of a randomized controlled crossover study. Gynecol Obstet Invest 75:230–234
Schäfer W, Abrams P, Liao L et al (2002) Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies. Neurourol Urodyn 21:261–274
Maynard FM Jr, Bracken MB, Creasey G et al (1997) International standards for neurological and functional classification of spinal cord injury American spinal injury association. Spinal Cord 35:266–274
Abrams P, Cardozo L, Fall M et al (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Neurourol Urodyn 21:167–178
Gaziev G, Topazio L, Iacovelli V et al (2013) Percutaneous tibial nerve stimulation (PTNS) efficacy in the treatment of lower urinary tract dysfunctions: a systematic review. BMC Urol 13:61–71
Schurch B, Denys P, Kozma CM et al (2007) Reliability and validity of the incontinence quality of life questionnaire in patients with neurogenic urinary incontinence. Arch Phys Med Rehabil 88:646–652
Krebs J, Pannek J (2013) Effects of solifenacin in patients with neurogenic detrusor overactivity as a result of spinal cord lesion. Spinal Cord 51:306–309
Groen J, Bosch JL (2001) Neuromodulation techniques in the treatment of the overactive bladder. BJU Int 87:723–731
Burks FN, Bui DT, Peters KM (2010) Neuromodulation and the neurogenic bladder. Urol Clin N Am 37:559–565
Zhang EJSC, Horwinski ER, Lytton B (1983) Treatment of motor and sensory detrusor instability by electrical stimulation. J Urol 129:78–79
de Seze M, Raibaut P, Gallien P (2011) Transcutaneous posterior tibial nerve stimulation for treatment of the overactive bladder syndrome in multiple sclerosis: results from a multicenter prospective study. Neurourol Urodyn 30:306–311
Acknowledgments
This study was supported by China National Technology R&G Program, No. 2012BAI34B02. All experiments were performed at the department of urology of the China Rehabilitation Research Center, Beijing, China. The authors would like to express special thanks to Mr. Chen Jian for technical support and Dr. Ju Lu for the valuable discussions.
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chen, G., Liao, L. & Li, Y. The possible role of percutaneous tibial nerve stimulation using adhesive skin surface electrodes in patients with neurogenic detrusor overactivity secondary to spinal cord injury. Int Urol Nephrol 47, 451–455 (2015). https://doi.org/10.1007/s11255-015-0911-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11255-015-0911-6