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IgG4-related tubulointerstitial nephritis presenting with psychiatric manifestations and skin lesions

  • Nephrology - Case report
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Abstract

We describe a 21-year male with mood disorder on lithium therapy and psoriasis-like skin lesions presenting with rapidly progressive renal failure. The kidney biopsy showed acute tubulointerstitial nephritis with immunoglobulin G4-positive plasma cell infiltration. He was started on oral steroids with a provisional diagnosis of IgG4-related tubulointerstitial nephritis. All dermatological, psychiatric and renal manifestations dramatically improved, and he was taken off lithium. He had a relapse of his psychiatric symptoms on stopping steroids, and they again responded to steroids.

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Authors and Affiliations

  1. Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Raja Ramachandran, Venkatesh Rajakumar, Vivek Kumar, Manish Rathi, Harbir S. Kohli, Vinay Sakhuja & Vivekanand Jha

  2. Department of Paediatric Allergy and Immunology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Amit Rawat

  3. Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Ritambhra Nada

Authors
  1. Raja Ramachandran
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  2. Venkatesh Rajakumar
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  3. Amit Rawat
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  4. Ritambhra Nada
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  5. Vivek Kumar
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  6. Manish Rathi
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  7. Harbir S. Kohli
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  8. Vinay Sakhuja
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  9. Vivekanand Jha
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Correspondence to Vivekanand Jha.

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Ramachandran, R., Rajakumar, V., Rawat, A. et al. IgG4-related tubulointerstitial nephritis presenting with psychiatric manifestations and skin lesions. Int Urol Nephrol 46, 235–238 (2014). https://doi.org/10.1007/s11255-013-0447-6

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  • DOI: https://doi.org/10.1007/s11255-013-0447-6

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