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An unusual cause of membranous glomerulonephritis in a patient with HIV

  • Nephrology – Case Report
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Abstract

A 68-year old Caucasian male with a past medical history of human immunodeficiency virus (HIV) infection presented with acute oliguric renal failure and maculopapular rash. Renal biopsy demonstrated extensive foot process effacement as well as confluent small subepithelial electron-dense deposits, which is diagnostic of membranous glomerulonephritis. Subsequent serological tests showed venereal disease research laboratory test was positive in both serum and cerebral spinal fluid. Following penicillin treatment, the patient’s creatinine returned to baseline 4 weeks later. Secondary membranous glomerulonephritis caused by syphilis in patients with HIV is discussed.

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Authors and Affiliations

  1. Renal Division, Washington University School of Medicine, 8126, 660 S. Euclid Ave., St. Louis, MO, 63110, USA

    Ying Maggie Chen & Aubrey R. Morrison

  2. Infectious Diseases Division, Washington University School of Medicine, St. Louis, MO, USA

    Luis A. Marcos & Thomas H. Steinberg

  3. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA

    Helen Liapis

Authors
  1. Ying Maggie Chen
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  2. Luis A. Marcos
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  3. Helen Liapis
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  4. Thomas H. Steinberg
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  5. Aubrey R. Morrison
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Corresponding author

Correspondence to Aubrey R. Morrison.

Additional information

Ying Maggie Chen and Luis A. Marcos contributed equally to this work.

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Chen, Y.M., Marcos, L.A., Liapis, H. et al. An unusual cause of membranous glomerulonephritis in a patient with HIV. Int Urol Nephrol 44, 983–986 (2012). https://doi.org/10.1007/s11255-011-9945-6

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  • DOI: https://doi.org/10.1007/s11255-011-9945-6

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