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Hemodialysis duration impairs food intake and nutritional parameters in chronic kidney disease patients

  • Nephrology – Original Paper
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Abstract

Introduction

The aim of this study was to evaluate the effect of hemodialysis (HD) duration on food intake and nutritional markers in patients with chronic kidney disease (CKD).

Methods

Twenty CKD patients received maintenance HD over a 9-year period. At the beginning of the study (T0) and at 3-year intervals (T1, T2, and T3) during the 9-year follow-up, a nutritional survey using the 24-h recall and record method was repeated for 4 days, and the blood samples were drawn. The results from T0 were used as references. Nutritional status was assessed through food intake, nutritional markers (urea, uric acid, creatinine, cholesterol, total protein, and albumin), and anthropometric measurements (height, dry weight, and body mass index).

Results

HD duration was correlated with energy intake (r = −0.89, P < 0.01), protein intake (r = −0.50, P < 0.05), and body mass index (r = −0.50, P < 0.05). Albuminemia decreased over time. Reduced carbohydrate intakes were noted in patients at T1 (−8%), T2 (−38%), and T3 (−59%) with decreased fiber intakes. Lipid intake was diminished by 11, 17, and 25% in patients, respectively, at T1, T2, and T3. The consumption of milk and dairy products, meats, fish, eggs, fruits, vegetables, and fat was reduced at T1, T2, and T3. In conclusion, long-term HD fails to correct undernutrition caused by CKD. Long-term dialysis complications could be reduced with preventive measures, including the use of biocompatible membranes and high-dose dialysis. Consequently, patients could experience a decreased prevalence of protein-energy malnutrition.

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References

  1. Shinaberger CS, Kilpatrick RD, Regidor DL et al (2006) Longitudinal associations between dietary protein intake and survival in hemodialysis patients. Am J Kidney Dis 48:37–49

    Article  PubMed  Google Scholar 

  2. Dukkipati R, Kopple JD (2009) Causes and prevention of protein-energy wasting in chronic kidney failure. Semin Nephrol 29(1):39–49

    Article  PubMed  Google Scholar 

  3. De Mutsert R, Grootendorst DC, Axelsson J et al (2008) Excess mortality due to interaction between protein-energy wasting, inflammation and cardiovascular disease in chronic dialysis patients. Nephrol Dial Transplant 23(9):2957–2964

    Article  PubMed  Google Scholar 

  4. Kovesdy CP, Kalantar-Zadeh K (2009) Why is protein-energy wasting associated with mortality in chronic kidney disease? Semin Nephrol 29(1):3–14

    Article  PubMed  CAS  Google Scholar 

  5. Leavey SF, Strawderman RL, Young EW et al (2000) Cross-sectional and longitudinal predictors of serum albumin in hemodialysis patients. Kidney Int 58:2119–2128

    Article  PubMed  CAS  Google Scholar 

  6. McDonald SP, Marshall MR, Johnson DW et al (2009) Relationship between dialysis modality and mortality. J Am Soc Nephrol 20(1):155–163

    Article  PubMed  Google Scholar 

  7. Eknoyan G, Beck GJ, Cheung AK et al (2002) Hemodialysis (HEMO) Study Group. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 347:2010–2019

    Article  PubMed  Google Scholar 

  8. Port FK, Ashby VB, Dhingra RK et al (2002) Dialysis dose and body mass index are strongly associated with survival in hemodialysis patients. J Am Soc Nephrol 13:1061–1066

    PubMed  Google Scholar 

  9. GENI 6.0 (2000) Gestion d’Enquêtes Nutritionnelles Informatisées. Software for Windows. Micro 6. Nancy, France

    Google Scholar 

  10. Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with the folin reagent. J Biol Chem 193:265–275

    PubMed  CAS  Google Scholar 

  11. Daugirdas JT (1990) Rapid method for estimating Kt/V: three formulas compared. ASAIO Trans 36:362–364

    Google Scholar 

  12. Mehrotra R, Kopple JD (2001) Nutritional management of maintenance dialysis patients: why aren’t we doing better? Annu Rev Nutr 21:343–379

    Article  PubMed  CAS  Google Scholar 

  13. Burrowes JD, Cockram DB, Dwyer JT et al (2002) Cross-sectional relationship between dietary protein and energy intake, nutritional status, functional status, and comorbidity in older versus younger hemodialysis patients. J Ren Nutr 12:87–95

    Article  PubMed  Google Scholar 

  14. Dobell E, Chan M, Williams P et al (1993) Food preferences and food habits of patients with chronic renal failure undergoing dialysis. J Am Diet Assoc 93:1129–1135

    Article  PubMed  CAS  Google Scholar 

  15. Chazot C, Laurent G, Charra B et al (2001) Malnutrition in long-term haemodialysis survivors. Nephrol Dial Transplant 16:61–69

    Article  PubMed  CAS  Google Scholar 

  16. Bazzi C, Arrigo G, Luciani L et al (1995) Clinical features of 24 patients on regular hemodialysis treatment for 16–23 years a single unit. Clin Nephrol 44:96–107

    PubMed  CAS  Google Scholar 

  17. Marcén R, Teruel JL, Angel de la Cal M et al (1997) The impact of malnutrition in morbidity and mortality in stable haemodialysis patients. Nephrol Dial Transplant 12:2324–2331

    Article  PubMed  Google Scholar 

  18. Friedman AN, Fadem SZ (2010) Reassessment of albumin as a nutritional marker in kidney disease. J Am Soc Nephrol 21(2):223–230

    Article  PubMed  CAS  Google Scholar 

  19. Mekki K, Prost J, Remaoun M et al (2009) Long term hemodialysis aggravates lipolytic activity reduction and very low density, low density lipoproteins composition in chronic renal failure patients. BMC Cardiovascular Disord 9(41):1–8

    Google Scholar 

  20. Leon JB, Majerle AD, Soinski JA et al (2001) Can a nutrition intervention improve albumin levels among hemodialysis patients? A pilot study. J Ren Nutr 11:9–15

    Article  PubMed  CAS  Google Scholar 

  21. Jager KJ, Merkus MP, Huisman RM et al (2001) The NECOSAD Study Group. Nutritional status over time in hemodialysis and peritoneal dialysis. J Am Soc Nephrol 12:1272–1279

    PubMed  CAS  Google Scholar 

  22. Locatelli F, Mastrangelo F, Redaelli B et al (1996) Effects of different membranes and dialysis technologies on patients treatment tolerance and nutritional parameters. The Italian Cooperative Dialysis Study Group. Kidney Int 50:1293–1302

    Article  PubMed  CAS  Google Scholar 

  23. Mehrotra R, Berman N, Alistwani A et al (2002) Improvement of nutritional status after initiation of maintenance hemodialysis. Am J Kidney Dis 40:133–142

    Article  PubMed  Google Scholar 

  24. Nakao T, Matsumoto H, Okada T et al (2003) Nutritional management of dialysis patients: balancing among nutrient intake, dialysis dose, and nutritional status. Am J Kidney Dis 41:S133–S136

    Article  PubMed  Google Scholar 

  25. Spanner E, Suri R, Heidenheim AP et al (2003) The impact of quotidian hemodialysis on nutrition. Am J Kidney Dis 42:30–35

    Article  PubMed  Google Scholar 

  26. Azar AT, Wahba K, Mohamed AS et al (2007) Association between dialysis dose improvement and nutritional status among hemodialysis patients. Am J Nephrol 27(2):113–119

    Article  PubMed  Google Scholar 

  27. Teixeira Nunes F, de Campos G, Xavier de Paula SM et al (2008) Dialysis adequacy and nutritional status of hemodialysis patients. Hemodial Int 12(1):45–51

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Laboratoire de Nutrition Clinique et Métabolique, Département de Biologie. Faculté des Sciences, Université d’Oran, 31100, Es-Sénia, Algeria

    Khedidja Mekki & Malika Bouchenak

  2. Service de Néphrologie-Hémodialyse, Centre Hospitalo-Universitaire de Sidi Bel Abbès, Sidi Bel Abbès, Algeria

    Mustapha Remaoun

  3. UPRES Lipides & Nutrition, Faculté des Sciences Gabriel, Université de Bourgogne, EA.2422, 6 Bd Gabriel, 21000, Dijon, France

    Jacques Belleville

Authors
  1. Khedidja Mekki
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  2. Mustapha Remaoun
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  3. Jacques Belleville
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  4. Malika Bouchenak
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Correspondence to Khedidja Mekki.

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Mekki, K., Remaoun, M., Belleville, J. et al. Hemodialysis duration impairs food intake and nutritional parameters in chronic kidney disease patients. Int Urol Nephrol 44, 237–244 (2012). https://doi.org/10.1007/s11255-010-9875-8

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  • DOI: https://doi.org/10.1007/s11255-010-9875-8

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