Abstract
Bosniak classification system is the only preoperative diagnostic tool that has proven its efficiency in the management of complex renal cystic masses. However, it is reader dependent, despite its clear definition of each category. The overall incidence of malignancy in each category did not change significantly over the past 20 years. Current limitations are interobserver variability among readers and a fact that a significant proportion of Bosniak III masses have benign character. The goal is to depict these masses preoperatively and spare the patients of unnecessary surgeries, which raises the question: What particular findings will help in differentiating a Bosniak IIF lesion from a Bosniak III lesion? Do we need to define critical variables that could improve accuracy of Bosniak classification by developing a future nomogram or risk calculator? Some radiologists and urologists erroneously tend to group Bosniak II and IIF in one category and observe them regularly. It seems that radiographic growth itself is insufficient factor for intervention. The change of internal architecture and presence of enhancement play the most important role in depicting malignant lesions during the time frame of active surveillance.
Similar content being viewed by others
References
Israel GM, Bosniak MA (2005) An update on the Bosniak classification system. Urology 66(3):484–488
Israel GM, Hindman N, Bosniak MA (2004) Evaluation of cystic masses: comparison of CT and MR imaging by using the Bosniak classification system. Radiology 231(2):365–371
Israel GM, Bosniak MA (2003) Calcification in cystic renal masses: is it important in diagnosis? Radiology 226:47–521
Isreal GM, Bosniak MA (2003) Follow-up CT of moderately complex cystic lesions of the kidney (Bosniak category IIF). AJR 181:627–633
Gabr AH, Gdor Y, Roberts WW, Wolf JS Jr (2008) Radiographic surveillance of minimally and moderately complex renal cysts. BJU Int 103:1116–1119
O’Malley RL, Godoy G, Hecht EM, Stifelman MD, Taneja SS (2009) Bosniak category IIF designation and surgery for complex renal cysts. J Urol 182:1091–1095
Weibl P, Lutter I, Breza J (2006) Follow-up of complex cystic lesions of the kidney Bosniak type II/IIF. Eur Urol Suppl 5(2):70
Wolf J Jr (1998) Evaluation and management of solid and cystic renal masses. J Urol 159(4):1120–1133
Bellman GC, Yamguchi R, Kaswick J (1995) Laparoscopic evaluation of indeterminate renal cysts. Urology 45(6):1066–1070
Koga S, Nishikido M, Inuzuka S, Sakamoto IHayashi T, Hayashi K, Saito Y, Kanetake H (2000) An evaluation of Bosniak classification of cystic renal masses. BJU Int 86:607–609
Spaliviero M, Herts BR, Magi-Galluzzi C, Xu M, Desai M, Kaouk J, Tucker K, Steinberg AP, Gill I (2005) Laparoscopic partial nephrectomy for cystic masses. J Urol 714:614–619
Song Ch, Min GU, Song K, Kim JK, Hong B, Kim CS, Hanjong A (2009) Differential diagnosis of complex cystic renal mass using multiphase computerized tomography. J Urol 181(6):2446–2450
Bosniak MA (1993) Problems in the radiologic diagnosis of renal parenchymal tumors. In: Olsson CA, Sawczuk IS (eds) The urologic clinics of North America. Saunders, Philadelphia, pp 217–230
Brenner DJ, Hall EJ (2007) Computed tomography—an increasing source of radiation exposure. New Engl J Med 357(22):2277–2284
Brown WC, Amis ES Jr, Kaplan SA, Blaivas JG, Axelrod SL (1989) Renal cystic lessions: predictive value of preoperative computerized tomography. J Urol 141:426A
Aronson S, Frayier HA, Baluch JD, Hartman DS, Christenson PJ (1991) Cystic renal masses: usefulness of the Bosniak classification. Urol Radiol 13(2):83–90
Cloix P, Martin X, Pangaud C, Marechal JM, Bouvier R, Barat D, Dubernard JM (1996) Surgical management of complex renal cysts: a series of 32 cases. J Urol 3:564–570
Wilson TE, Doelle EA, Cohan RH, Wojno K, Korobkin M (1996) Cystic renal masses: a reevaluation of the usefulness of the Bosniak classification system. Acad Radiol 3:564–570
Siegel CL, McFarland EG, Brink JA, Fisher AJ, Humphrey P, Heiken JP (1997) CT of cystic renal masses: analysis of diagnostic performance and interobserver variation. AJR Am J Roentgenol 169:813–818
Bielsa GO, Arango TO, Cortadellas AR, Castro SR, Griñó Garreta J, Gelabert-Mas A (1999) The preoperative diagnosis of complex renal cystic masses. Arch Esp Urol 52(1):19–25
Curry NS, Cochran ST, Bissada NK (2000) Cystic renal masses: accurate Bosniak classification requires adequate renal CT. AJR Am J Ronentgenol 175:339–342
Limb J, Santiago L, Kaswick J, Bellman GC (2002) Laparoscopic evaluation of indeterminate renal cysts:long-term follow-up. J Endourol 16(2):79–82
Weibl P, Klatte T, Kollarik B, Geryk B, Schueller G, Marberger M, Remzi M (2010) Complex renal cystic masses: interpersonal variability of Bosniak classification is significant—fact or fiction. Eur Urol Suppl 9(2):298
Quaia E, Bertolotto M, Cioffi V, Rossi A, Baratella E, Pizzolato R, Cova MA (2008) Comparison of contrast-enhanced sonography with unenhanced sonography and contrast enhanced CT in the diagnosis of malignancy in complex cystic renal masses. AJR 191:1239–1249
Remzi M, Marberger M (2009) Renal tumor biopsies for evaluation of small renal tumors: why, in whom, and how? Eur Urol 55(2):359–367
Harisinghani MG, Maher MM, Gervais DA, McGovern F, Hahn P, Jhaveri K, Varghese J, Mueller PR (2003) Incidence of malignancy in complex cystic renal masses (Bosniak category III): Should imaging- guided biopsy precede surgery? AJR 180:755–758
Lang EK, Macchia RJ, Gayle B, Richter F, Watson RA, Thomas R, Myers L (2002) CT-guided biopsy of indeterminate renal cystic masses (Bosniak 3 and 2F): accuracy and impact on clinical management. Eur Radiol 12:2518–2524
Lechevalier E, Andre M, Barriol D, Daniel L, Eghazarian C, Fromont MD, Rossi D, Coulange C (2000) Fine-needle percutaneous biopsy of renal masses with helical CT guidance. Radiology 216:506–510
http://clinicaltrials.gov/show/NCT00491621 Study ID Number: 0501106
Conflicts of interest
I hereby certify that the manuscript or portions thereof are not under considerations by another journal or electronic publication and have not been previously published. Authors fully support this statement. The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Weibl, P., Klatte, T., Waldert, M. et al. Complex renal cystic masses: current standards and controversies. Int Urol Nephrol 44, 13–18 (2012). https://doi.org/10.1007/s11255-010-9864-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11255-010-9864-y