Abstract
We report a case of endobronchial metastasis from prostate adenocarcinoma. A patient with a history of prostate cancer under complete androgen blockade presented to the respiratory department complaining of dyspnea and dry coughing. Flexible bronchoscopy showed multiple polypoid lesions in the tracheobronchial tree and the immunohistochemical studies on the biopsy specimen determined the diagnosis. The patient was treated with paclitaxel, estramustine phosphate and carboplatine, and experienced symptoms suppression. To our knowledge, this is the first case of endobronchial metastasis of a patient with androgen refractory prostate cancer without any evidence of extrathoracic metastasis. The current report also emphasises the need for a multidisciplinary approach for cases of endobronchial metastases, with the collaboration of pneumologists, urologists, pathologists and oncologists.
Similar content being viewed by others
References
Sørensen JB (2004) Endobronchial metastases from extrapulmonary solid tumors. Acta Oncol 43:73–79
Katsimbri PP, Bamias AT, Froudarakis ME, Peponis IA, Constantopoulos SH, Pavlidis NA (2000) Endobronchial metastases secondary to solid tumors: report of eight cases and review of the literature. Lung Cancer 28:163–170
Salud A, Porcel JM, Rovirosa A, Bellmunt J (1996) Endobronchial metastatic disease: analysis of 32 cases. J Surg Oncol 62:249–252
Long MA, Husband JE (1999) Features of unusual metastases from prostate cancer. Br J Radiol 72:933–941
Chitale S, Webb R, MacIver D, Peat D (in press) Multifocal symptomatic intracerebral metastases as the first manifestation of prostatic carcinoma: a report and literature review. Int Urol Nephrol doi:10.1007/s11255-007-9315-6
Gunlusoy B, Arslan M, Selek E, Sayhan HS, Minareci S, Cicek S (2004) A case report: renal metastasis of prostate cancer. Int Urol Nephrol 36:555–557
Grenader T, Shavit L, Lossos A, Pizov G, Wygoda M (2007) Brain metastases: a rare initial presentation of prostate cancer. Int Urol Nephrol 39:537–539
Carleton J, van der Riet P, Dahm P (2005) Metastatic prostate cancer presenting as an asymptomatic neck mass. Prostate Cancer Prostatic Dis 8(3):293–295
Scherz H, Schmidt JD (1986) Endobronchial metastasis from prostate carcinoma. Prostate 8:319–324
Kenny JN, Smith WL, Brawer MK (1988) Endobronchial metastases from prostatic carcinoma. Ann Thorac Surg 45:223–224
Taylor H, Braude S (1990) Lobar collapse due to endobronchial metastatic prostatic carcinoma: re-expansion with antiandrogen treatment. Thorax 45:66–67
Lee DW, Ro JY, Sahin AA, Lee JS, Ayala AG (1990) Mucinous adenocarcinoma of the prostate with endobronchial metastasis. Am J Clin Pathol 94:641–645
Stranzl H, Gabor S, Mayer R, Prettenhofer U, Wurzinger G, Hackl A (2002) Fractionated intraluminal HDR 192Ir brachytherapy as palliative treatment in patients with endobronchial metastases from non-bronchogenic primaries. Strahlenther Onkol 178:442–445
Heitmiller RF, Marasco WJ, Hruban RH, Marsh BR (1993) Endobronchial metastasis. J Thorac Cardiovasc Surg 106:537–542
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gerogianni, I., Gravas, S., Papadopoulos, D. et al. Endobronchial metastasis from prostate cancer. Int Urol Nephrol 40, 961–964 (2008). https://doi.org/10.1007/s11255-008-9369-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11255-008-9369-0