Abstract
In VHL syndrome, renal cell carcinoma is distinctive for its early age of onset, for its bilateral and multifocal involvement. Synchronous solitary urinary bladder metastasis from renal cell carcinoma is extremely rare. We report an unusual case of VHL with bilateral multicentric renal cell carcinoma and synchronous solitary urinary bladder metastasis. To the best of our knowledge this is the first case reported in literature with this combination.
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References
Neumann HP and Zbar B (1997). Renal cyst, renal cancer and VHL disease. Kidney Int 51: 16–26
Ziade J and Cipolla B (1994). Acta Urol Belg 62(4): 45–48
Neumann HPH and Weistler OD (1991). Clustering of features of VHL. Evidence of a complex genetic locus. Lancet 337: 1052
Linehan WM, Lemna MJ and Zbar B (1995). Identification of VHL gene, its role in renal cancer. JAMA 273: 564–570
Gallmetzer J (2000). Urologe A 39(1): 52–54
Shiraishi K (2003). Int J Urol 10(3): 453–455
Manabu M. (2002). Urology 60(5): 911–912
Goldfarb DA, Neumann HP, Penn I, Novick AC. Results of renal transplantation 1997; 64: 1726
Novick AC, Streem SB. Long term follow up after nephron sparing surgery for renal cell carcinoma in VHL disease J Urol 147 1488
Fry Denberg M and Male Zincke KR H (1993). Conservative renal surgery for renal cell carcinoma in VHL. J Urol 149: 461
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Dogra, P., Kumar, A. & Singh, A. An unusual case of Von Hipple Lindau (VHL) syndrome with bilateral mutlicentric renal cell carcinoma with synchronous solitary urinary bladder metastasis. Int Urol Nephrol 39, 11–14 (2007). https://doi.org/10.1007/s11255-006-6656-5
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DOI: https://doi.org/10.1007/s11255-006-6656-5