Skip to main content
Log in

Usefulness of an immunochromatographical assay, PSA Rapid Test as a primary screening test for prostate cancer

  • Research Article
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Background

The recent rapid increase of mass screening for prostate cancer by measuring PSA in Japan will increase the economic burden to the healthcare system. PSA Rapid Test (PRT) is a simple inexpensive test. The usefulness of PRT as a primary screening test for prostate cancer was evaluated.

Methods

When we conducted educational lectures for prostate cancer in our city, screening for prostate cancer using PRT was offered to the male participants. The results of the tests were handed to participants in writing at the end of the lectures. When the results were judged as positive, letters of referral to our institute were enclosed.

Results

One hundred and fourteen (18.6%) of 614 men were judged as positive by PRT. Of the 114 men with positive PRT, 73 (64%) visited our institution. Finally, 37 men underwent a transrectal prostate biopsy and a diagnosis of prostate cancer was made in 21 men (3.4% of all participants). The total costs for the PSA tests in this study were summed to be approximately $2,300, while they would be approximately $9,200 if all participants had undergone screening using the conventional quantitative method from the outset.

Conclusion

PRT is a low-cost method to detect patients with prostate cancer. We believe the PRT is useful as an initial screening test for detecting prostate cancer and that the combination of the PRT and more precise quantitative testing would be a reasonable way to reduce the cost and achieve high detection rate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Statistics and Information Department, M.o.L., Health and Welfare: Vital population Statistics in Heisei 15 (2003) in Japan. Table 5-24. Mortality and mortality rate per 100,000 from the standpoint of the etiology, http://www.dbtk.mhlw.go.jp/toukei/data/010/2003/toukeihyou/0004652/t0098908/mc240_001.html

  2. Catalona WJ, Richie JP, Ahmann FR, et al (1994) Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men. J Urol 151(5):1283–1290

    PubMed  CAS  Google Scholar 

  3. Rietbergen JB, Kranse R, Kirkels WJ, et al (1997) Evaluation of prostate-specific antigen, digital rectal examination and transrectal ultrasonography in population-based screening for prostate cancer: improving the efficiency of early detection. Br J Urol 79(Suppl 2):57–63

    PubMed  Google Scholar 

  4. Kobayashi M, Takezawa Y, Nakata S, et al (2000) The result of mass screening of 1997 for prostatic cancer in Isesaki City. Nippon Hinyokika Gakkai Zasshi 91(1):1–7

    PubMed  CAS  Google Scholar 

  5. Kanayama HO, Kagawa S, Utsunomiya M, et al (2004) Mass screening for prostate cancer in Tokushima City: the results of 2001. Nippon Hinyokika Gakkai Zasshi 95(3):596–603

    PubMed  Google Scholar 

  6. Uchida K, Takeshima H, Akaza H, et al (2000) Screening for prostate cancer using prostate-specific antigen alone as a first-line checkup parameter: results of the health checkup system. Jpn J Clin Oncol 30(2):95–100

    Article  PubMed  CAS  Google Scholar 

  7. Ito K, Kubota Y, Banzai R, Yuasa H, Shimizu N, Kurokawa K, et al (1999) The present status, problems, and future of mass screening for prostate cancer in Gunma prefecture. The report of mass screening for prostate cancer study meeting in 1998. Kitakanto Med J 49:81–88

    Article  Google Scholar 

  8. Stephan C, Jung K, Brux B, et al (2000) ACT-PSA and complexed PSA elimination kinetics in serum after radical retropubic prostatectomy: proof of new complex forming of PSA after release into circulation. Urology 55(4):560–563

    Article  PubMed  CAS  Google Scholar 

  9. Brawer MK (2000) Prostate-specific antigen. Semin Surg Oncol 18(1):3–9

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kazushi Shigeno.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shigeno, K., Arichi, N., Yoneda, T. et al. Usefulness of an immunochromatographical assay, PSA Rapid Test as a primary screening test for prostate cancer. Int Urol Nephrol 38, 565–569 (2006). https://doi.org/10.1007/s11255-006-0086-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-006-0086-2

Keywords

Navigation