Skip to main content

Advertisement

SpringerLink
Log in

Hepatitis C virus related lymphoproliferative disorder in a renal transplant recipient

  • Case Report
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Posttransplant lymphoproliferative disorders (PTLD) are commonly caused by Ebstein-Barr Virus infection. The role of hepatitis C virus (HCV) in the genesis of lymphomas has been recognized recently. We report a HCV infected renal transplant recipient who developed PTLD 11 months after transplantation. Reduction of immunosuppression led to disappearance of viremia and clearance of PTLD. This is the first such report in the world literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. O Hermine F Lefrère J-P Bronowicki et al. (2002) ArticleTitleRegression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection N Engl J Med 347 89–94 Occurrence Handle12110736 Occurrence Handle1:CAS:528:DC%2BD38XltFGrurs%3D Occurrence Handle10.1056/NEJMoa013376

    Article  PubMed  CAS  Google Scholar 

  2. F Silvestri G Barillari R Fanin et al. (1998) ArticleTitleImpact of hepatitis C virus infection on clinical features, quality of life and survival of patients with lymphoplasmacytoid lymphoma/immunocytoma Ann Oncol 9 499–504 Occurrence Handle9653490 Occurrence Handle1:STN:280:DyaK1czhsleksA%3D%3D Occurrence Handle10.1023/A:1008265804550

    Article  PubMed  CAS  Google Scholar 

  3. E Zuckerman T Zuckerman AM Levine et al. (1997) ArticleTitleHepatitis C virus infection in patients with B-cell non-Hodgkin lymphoma Ann Intern Med 127 423–428 Occurrence Handle9312998 Occurrence Handle1:STN:280:ByiH2c%2Fgt1U%3D

    PubMed  CAS  Google Scholar 

  4. T Izumi R Sasaki S Tsunoda M Akutsu H Okamoto Y Miura (1997) ArticleTitleB cell malignancy and hepatitis C virus infection Leukemia 11 IssueIDSuppl 3 516–518 Occurrence Handle9209442

    PubMed  Google Scholar 

  5. A Buda A Caforio F Calabrese et al. (2000) ArticleTitleLymphoproliferative disorders in heart transplant recipients: role of hepatitis C virus (HCV) and Epstein-Barr virus (EBV) infection Transpl Int 13 IssueIDSuppl 1 S402–S405 Occurrence Handle11112042 Occurrence Handle10.1007/s001470050371

    Article  PubMed  Google Scholar 

  6. K McLaughlin S Wajstaub P Marotta P Adams DR Grant WJ Wall AM Jevnikar KS Rizkalla (2000) ArticleTitleIncreased risk for posttransplant lymphoproliferative disease in recipients of liver transplants with hepatitis C Liver Transpl 6 570–574 Occurrence Handle10980055 Occurrence Handle1:STN:280:DC%2BD3cvpsVOhsQ%3D%3D Occurrence Handle10.1053/jlts.2000.7578

    Article  PubMed  CAS  Google Scholar 

  7. C Hezode C Duvoux G Germanidis et al. (1999) ArticleTitleRole of hepatitis C virus in lymphoproliferative disorders after liver transplantation Hepatology 30 775–778 Occurrence Handle10462385 Occurrence Handle1:STN:280:DyaK1MzptFOqtQ%3D%3D Occurrence Handle10.1002/hep.510300314

    Article  PubMed  CAS  Google Scholar 

  8. C Duvoux GP Pageaux C Vanlemmens et al. (2002) ArticleTitleRisk factors for lymphoproliferative disorders after liver transplantation in adults: an analysis of 480 patients Transplantation 74 1103–1109 Occurrence Handle12438954 Occurrence Handle10.1097/00007890-200210270-00008

    Article  PubMed  Google Scholar 

  9. JS Pagano (2002) ArticleTitleViruses and lymphomas N Engl J Med 347 78–79 Occurrence Handle12110734 Occurrence Handle10.1056/NEJMp020056

    Article  PubMed  Google Scholar 

  10. Zuckerman (2001) ArticleTitleThe effect of antiviral therapy on t(14;18) translocation and immunoglobulin gene rearrangement in patients with chronic hepatitis C virus infection Blood 97 1555–1559 Occurrence Handle11238090 Occurrence Handle1:CAS:528:DC%2BD3MXitFaltro%3D Occurrence Handle10.1182/blood.V97.6.1555

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Nephrology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India

    A. N. Aravindan, Venkatesh Moger, Vinay Sakhuja, Harbir S. Kohli & Vivekanand Jha

  2. Hematology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh , India

    Neelam Varma

Authors
  1. A. N. Aravindan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Venkatesh Moger
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vinay Sakhuja
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Harbir S. Kohli
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Neelam Varma
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Vivekanand Jha
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vivekanand Jha.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aravindan, A.N., Moger, V., Sakhuja, V. et al. Hepatitis C virus related lymphoproliferative disorder in a renal transplant recipient. Int Urol Nephrol 38, 355–357 (2006). https://doi.org/10.1007/s11255-006-0050-1

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-006-0050-1

Keywords

Search

Navigation