Abstract
The aim of this study was to evaluate the effects of dose, start time, and application interval of recombinant bovine somatotropin (rbST) on performance, health, and reproduction parameters of crossbred Holstein × Gyr dairy cows (3/4 and 7/8). A 2 × 2 × 2 factorial study was designed to test the effects of application dose (250 mg rbST or 500 mg rbST), start of application (40 or 63 days in milk (DIM)), and application interval (12 or 14 days); 180 crossbred Holstein × Gyr cows were enrolled. Treatments with 500 mg rbST resulted in increased milk production, 3.5% fat-corrected milk (FCM), and energy-corrected milk (ECM). In the factorial design analysis, greater FCM, ECM, and milk solid production (kg/day) were observed when 500 mg rbST was started at 63 DIM, while 250 mg rbST resulted in greater milk production (kg/day), FCM, ECM, and milk solids (kg/day) when administered at 12-day intervals. Administration of 500 mg rbST resulted in an increase of days open and number of services per pregnancy (P = 0.01). Holstein × Gyr cows (3/4 and 7/8) presented a superior productive response to rbST when treated with 500 mg starting at 63 DIM and at 14-day intervals.
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The data that support the findings of this study are available upon request.
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Acknowledgements
The authors are thankful to the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Brasília, Brazil), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brasília, Brazil), the Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG, Belo Horizonte, Brazil), the Fundação de Apoio ao Ensino, Pesquisa e Extensão (FEPE, Belo Horizonte, Brazil), and the Universidade Federal de Minas Gerais (UFMG – Minas Gerais, Brazil) for the infrastructure and financial support. We also thank Fazenda Brejo Alegre for the infrastructure to conduct this study.
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SGC and ER gave the main idea. AMQL made the experimental design. BGC, BFS, and TSM performed the study. MNP performed the statistical analysis. BGC, MCL, and HCDN wrote the manuscript. SGC and BFS did the proof reading. All the authors revised and finalized the article.
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All procedures used were approved by the Animal Use Ethics Committee of Universidade Federal de Minas Gerais under the protocol number 230/2008.
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Campos, B.G., Lombardi, M.C., do Carmo Diniz Neto, H. et al. How to use recombinant bovine somatotropin in crossbred Holstein × Gyr (3/4 and 7/8) cows?. Trop Anim Health Prod 55, 63 (2023). https://doi.org/10.1007/s11250-023-03489-4
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DOI: https://doi.org/10.1007/s11250-023-03489-4