Skip to main content
Log in

Role of nanotechnology in animal production and veterinary medicine

  • Reviews
  • Published:
Tropical Animal Health and Production Aims and scope Submit manuscript

Abstract

Nanotechnology is the discipline and technology of small and specific things that are < 100 nm in size. Because of their extremely miniscule size, any changes in their chemical and physical structure may show higher reactivity and solubility than larger particles. Nanotechnology plays a vital role in every field of life. It is considered one of the most bleeding edge field of scientific research. It has already several applications in a myriad of disciplines while its application in the field of animal production and veterinary medicine is still experimental in nature. But, in recent years, the role of nanotechnology in the aforementioned fields of scientific inquiry has shown great progress. These days, nanotechnology has been employed to revolutionize drug delivery systems and diagnose atypical diseases. Applications of nanoparticle technology in the field of animal reproduction and development of efficacious vaccines have been at the forefront of scientific endeavors. Additionally, their impacts on meat and milk quality are also being judiciously inquired in recent decades. Veterinary nanotechnology has great potential to improve diagnosis and treatment, and provide new tools to this field. This review focuses on some noteworthy applications of nanoparticles in the field of animal production and their future perspectives.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

Data availability

Not applicable.

Code availability

Not applicable.

References

  • Adda, J., 2020. Preventing the spread of antibiotic resistance In:, AEA Papers and Proceedings,

  • Adeyeye, S.A.O., 2019. Food packaging and nanotechnology: safeguarding consumer health and safety Nutrition & Food Science, doi: https://doi.org/10.1108/NFS-01-2019-0020 (Emerald Publishing Limited)

    Article  Google Scholar 

  • Ahmadzada, T., Reid, G. and McKenzie, D.R., 2018. Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer. Biophysical reviews, 10, 69–86

    Article  CAS  Google Scholar 

  • Akbari, A., Lavasanifar, A. and Wu, J., 2017. Interaction of cruciferin-based nanoparticles with Caco-2 cells and Caco-2/HT29-MTX co-cultures. Acta biomaterialia, 64, 249–258 (England)

  • Akhavan, S., Assadpour, E., Katouzian, I. and Jafari, S.M., 2018. Lipid nano scale cargos for the protection and delivery of food bioactive ingredients and nutraceuticals Trends in Food Science & Technology, 74, 132–146 (Elsevier)

  • Albanese, A., Tang, P.S. and Chan, W.C.W., 2012. The effect of nanoparticle size, shape, and surface chemistry on biological systems Annual review of biomedical engineering, 14, 1–16 (Annual Reviews)

  • Alghuthaymi, M.A., Hassan, A.A., Kalia, A., Sayed El Ahl, R.M.H., El Hamaky, A.A.M., Oleksak, P., Kuca, K. and Abd-Elsalam, K.A., 2021. Antifungal Nano-Therapy in Veterinary Medicine: Current Status and Future Prospects

  • Altintas, Z., 2017. Biosensors and nanotechnology: applications in health care diagnostics, (John Wiley & Sons)

  • Aqil, F., Munagala, R., Jeyabalan, J., Agrawal, A.K., Kyakulaga, A.-H., Wilcher, S.A. and Gupta, R.C., 2019. Milk exosomes - Natural nanoparticles for siRNA delivery. Cancer letters, 449, 186–195 (Ireland)

  • AshaRani, P. V, Low Kah Mun, G., Hande, M.P. and Valiyaveettil, S., 2009. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS nano, 3, 279–290 (United States)

  • Azeredo, H.M.C. de, 2009. Nanocomposites for food packaging applications Food Research International, 42, 1240–1253

    Article  Google Scholar 

  • Bandara, N., Akbari, A., Esparza, Y. and Wu, J., 2018. Canola protein: a promising protein source for delivery, adhesive, and material applications Journal of the American Oil Chemists’ Society, 95, 1075–1090 (Wiley Online Library)

  • Barkalina, N., Charalambous, C., Jones, C. and Coward, K., 2014. Nanotechnology in reproductive medicine: Emerging applications of nanomaterials Nanomedicine: Nanotechnology, Biology and Medicine, 10, e921–e938

    Google Scholar 

  • Barkhordari, A., Hekmatimoghaddam, S., Jebali, A., Khalili, M.A., Talebi, A. and Noorani, M., 2013. Effect of zinc oxide nanoparticles on viability of human spermatozoa Iranian journal of reproductive medicine, 11, 767–771 (Research and Clinical Center for Infertility)

  • Bekere, H. and Husen, M., 2020. Review on the Composition of Milk of Different Farm Animal. American Journal of Pure and Applied Biosciences, https://doi.org/10.2139/ssrn.3713853

  • Bentolila, L.A., Ebenstein, Y. and Weiss, S., 2009. Quantum dots for in vivo small-animal imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 50, 493–496

    Article  CAS  Google Scholar 

  • Björkman, I., Röing, M., Sternberg Lewerin, S., Stålsby Lundborg, C. and Eriksen, J., 2020. Animal Production With Restrictive Use of Antibiotics to Contain Antimicrobial Resistance in Sweden-A Qualitative Study. Frontiers in veterinary science, 7, 619030

  • Boey, A. and Ho, H.K., 2020. All Roads Lead to the Liver: Metal Nanoparticles and Their Implications for Liver Health. Small (Weinheim an der Bergstrasse, Germany), 16, e2000153 (Germany)

  • Boulaiz, H., Alvarez, P.J., Ramirez, A., Marchal, J.A., Prados, J., Rodríguez-Serrano, F., Perán, M., Melguizo, C. and Aranega, A., 2011. Nanomedicine: application areas and development prospects International journal of molecular sciences, 12, 3303–3321 (Molecular Diversity Preservation International)

  • Bryła, M. and Trzcińska, M., 2015. Quality and fertilizing capacity of boar spermatozoa during liquid storage in extender supplemented with different antibiotics. Animal reproduction science, 163, 157–163 (Netherlands)

  • Carvalho, J.O., Silva, L.P., Sartori, R. and Dode, M.A.N., 2013. Nanoscale differences in the shape and size of X and Y chromosome-bearing bovine sperm heads assessed by atomic force microscopy PloS one, 8, e59387 (Public Library of Science)

  • Chakraborti, S., Mandal, A.K., Sarwar, S., Singh, P., Chakraborty, R. and Chakrabarti, P., 2014. Bactericidal effect of polyethyleneimine capped ZnO nanoparticles on multiple antibiotic resistant bacteria harboring genes of high-pathogenicity island. Colloids and surfaces. B, Biointerfaces, 121, 44–53 (Netherlands)

  • Chakravarthi, V.P. and Balaji, N., 2010. Applications of nanotechnology in veterinary medicine Veterinary World, 3, 477 (Veterinary World)

  • Cheeseman, S., Christofferson, A.J., Kariuki, R., Cozzolino, D., Daeneke, T., Crawford, R.J., Truong, V.K., Chapman, J. and Elbourne, A., 2020. Antimicrobial Metal Nanomaterials: From Passive to Stimuli-Activated Applications. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7, 1902913

  • Choi, S.-J., Oh, J.-M. and Choy, J.-H., 2010. Biocompatible nanoparticles intercalated with anticancer drug for target delivery: pharmacokinetic and biodistribution study. Journal of nanoscience and nanotechnology, 10, 2913–2916 (United States)

  • Cohen, Y., Ish-Shalom, S., Segal, E., Nudelman, O., Shpigelman, A. and Livney, Y.D., 2017. The bioavailability of vitamin D3, a model hydrophobic nutraceutical, in casein micelles, as model protein nanoparticles: human clinical trial results Journal of Functional Foods, 30, 321–325 (Elsevier)

  • Dervisevic, M., Alba, M., Prieto-Simon, B. and Voelcker, N.H., 2020. Skin in the diagnostics game: Wearable biosensor nano-and microsystems for medical diagnostics Nano Today, 30, 100828 (Elsevier)

  • Dhar, B.C. and Lee, N.Y., 2018. Lab-on-a-chip technology for environmental monitoring of microorganisms Biochip Journal, 12, 173–183 (Springer)

  • Dilbaghi, N., Kaur, H., Kumar, R., Arora, P. and Kumar, S., 2013. Nanoscale device for veterinary technology: trends and future prospective Advanced Materials Letters, 4, 175–184

    Article  Google Scholar 

  • Dos Santos, C.A., Ingle, A.P. and Rai, M., 2020. The emerging role of metallic nanoparticles in food. Applied microbiology and biotechnology, 104, 2373–2383 (Germany)

  • Durfey, C.L., Swistek, S.E., Liao, S.F., Crenshaw, M.A., Clemente, H.J., Thirumalai, R.V.K.G., Steadman, C.S., Ryan, P.L., Willard, S.T. and Feugang, J.M., 2019. Nanotechnology-based approach for safer enrichment of semen with best spermatozoa. Journal of animal science and biotechnology, 10, 14

    Article  Google Scholar 

  • DUTTA, T.K., YADAV, S.K. and CHATTERJEE, A., 2019. ANTIBIOTICS AS FEED ADDITIVES FOR LIVESTOCK: HUMAN HEALTH CONCERNS Indian J. Anim. Hlth, 58, 121–136

  • El-Sayed, A. and Kamel, M., 2020a. Advanced applications of nanotechnology in veterinary medicine. Environmental science and pollution research international, 27, 19073–19086 (Germany)

  • El-Sayed, A. and Kamel, M., 2020b. Advances in nanomedical applications: diagnostic, therapeutic, immunization, and vaccine production Environmental Science and Pollution Research, 27, 19200–19213

  • El-Sayed, A. and Kamel, M., 2021. Bovine mastitis prevention and control in the post-antibiotic era Tropical animal health and production, 53, 1–16 (Springer)

  • El Sabry, M.I., McMillin, K.W. and Sabliov, C.M., 2018. Nanotechnology considerations for poultry and livestock production systems–a review Annals of Animal Science, 18, 319 (De Gruyter Poland)

  • Farjadian, F., Ghasemi, A., Gohari, O., Roointan, A., Karimi, M. and Hamblin, M.R., 2019. Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities Nanomedicine, 14, 93–126 (Future Medicine)

  • Fatima, F., Siddiqui, S. and Khan, W.A., 2020. Nanoparticles as Novel Emerging Therapeutic Antibacterial Agents in the Antibiotics Resistant Era. Biological trace element research, doi: https://doi.org/10.1007/s12011-020-02394-3 (United States)

    Article  PubMed  Google Scholar 

  • Feugang, J.M., Youngblood, R.C., Greene, J.M., Fahad, A.S., Monroe, W.A., Willard, S.T. and Ryan, P.L., 2012. Application of quantum dot nanoparticles for potential non-invasive bio-imaging of mammalian spermatozoa Journal of Nanobiotechnology, 10, 45

    Article  CAS  Google Scholar 

  • Formiga, F.R., 2021. Nanotechnology and Veterinary Drug/Vaccine Delivery Pharmaceutical Nanotechnology, 9, 4 (Bentham Science Publishers)

  • Galldiks, N., Stoffels, G., Ruge, M.I., Rapp, M., Sabel, M., Reifenberger, G., Erdem, Z., Shah, N.J., Fink, G.R., Coenen, H.H. and Langen, K.-J., 2013. Role of O-(2–18F-fluoroethyl)-L-tyrosine PET as a diagnostic tool for detection of malignant progression in patients with low-grade glioma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54, 2046–2054 (United States)

  • Gheibi Hayat, S.M. and Darroudi, M., 2019. Nanovaccine: A novel approach in immunization. Journal of cellular physiology, 234, 12530–12536 (United States)

  • Głąb, T.K. and Boratyński, J., 2017. Potential of Casein as a Carrier for Biologically Active Agents. Topics in current chemistry (Cham), 375, 71

    Article  Google Scholar 

  • Goel, S., England, C., Chen, F. and Cai, W., 2016. Positron Emission Tomography and Nanotechnology: A Dynamic Duo for Cancer Theranostics Advanced drug delivery reviews, 113

  • Gonzales-Eguia, A., Fu, C.-M., Lu, F.-Y. and Lien, T.-F., 2009. Effects of nanocopper on copper availability and nutrients digestibility, growth performance and serum traits of piglets Livestock Science, 126, 122–129 (Elsevier)

  • Haben Fesseha, Mvs., 2020. Nanotechnology and its Application in Animal Production: A Review

  • Han, C., Qi, C.M., Zhao, B.K., Cao, J., Xie, S.Y., Wang, S.L. and Zhou, W.Z., 2009. Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. Journal of veterinary pharmacology and therapeutics, 32, 116–123 (England)

  • Hanrahan, L., McHugh, N., Hennessy, T., Moran, B., Kearney, R., Wallace, M. and Shalloo, L., 2018. Factors associated with profitability in pasture-based systems of milk production. Journal of dairy science, 101, 5474–5485 (United States)

  • Hargreaves, C.A., Rogers, S., Hills, F., Rahman, F., Howell, R.J. and Homa, S.T., 1998. Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. Human reproduction (Oxford, England), 13, 1878–1886 (England)

  • Hasanen, E., Elqusi, K., ElTanbouly, S., Hussin, A.E., AlKhadr, H., Zaki, H., Henkel, R. and Agarwal, A., 2020. PICSI vs. MACS for abnormal sperm DNA fragmentation ICSI cases: a prospective randomized trial. Journal of assisted reproduction and genetics, 37, 2605–2613

    Article  Google Scholar 

  • Hassan, M.M., El Zowalaty, M.E., Lundkvist, Å., Järhult, J.D., Khan Nayem, M.R., Tanzin, A.Z., Badsha, M.R., Khan, S.A. and Ashour, H.M., 2021. Residual antimicrobial agents in food originating from animals. Trends in food science & technology, 111, 141–150

    Article  CAS  Google Scholar 

  • He, W., Hosseinkhani, H., Mohammadinejad, R., Roveimiab, Z., Hueng, D., Ou, K. and Domb, A.J., 2014. Polymeric nanoparticles for therapy and imaging Polymers for advanced technologies, 25, 1216–1225 (Wiley Online Library)

  • Hill, E.K. and Li, J., 2017. Current and future prospects for nanotechnology in animal production. Journal of animal science and biotechnology, 8, 26

    Article  Google Scholar 

  • Hyman, P. and Denyes, J., 2021. Bacteriophages in nanotechnology: history and future Bacteriophages: Biology, Technology, Therapy, 657–687 (Springer)

  • Jackson, T.C., Patani, B.O. and Ekpa, D.E., 2017. Nanotechnology in diagnosis: a review Advances in Nanoparticles, 6, 93–102 (Scientific Research Publishing)

  • Jafari, S.M. and McClements, D.J., 2017. Nanotechnology Approaches for Increasing Nutrient Bioavailability. Advances in food and nutrition research, 81, 1–30 (United States)

  • Jamali, H., Barkema, H.W., Jacques, M., Lavallée-Bourget, E.-M., Malouin, F., Saini, V., Stryhn, H. and Dufour, S., 2018. Invited review: Incidence, risk factors, and effects of clinical mastitis recurrence in dairy cows Journal of Dairy Science, 101, 4729–4746

  • Jamkhande, P.G., Ghule, N.W., Bamer, A.H. and Kalaskar, M.G., 2019. Metal nanoparticles synthesis: An overview on methods of preparation, advantages and disadvantages, and applications Journal of Drug Delivery Science and Technology, 53, 101174 (Elsevier)

  • Johnson, L., Duschl, A. and Himly, M., 2020. Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research. Vaccines, 8

  • Kailasa, S.K., Mehta, V.N., Koduru, J.R., Basu, H., Singhal, R.K., Murthy, Z.V.P. and Park, T.-J., 2021. An overview of molecular biology and nanotechnology based analytical methods for the detection of SARS-CoV-2: promising biotools for the rapid diagnosis of COVID-19. The Analyst, 146, 1489–1513 (England)

  • Kargozar, S. and Mozafari, M., 2018. Nanotechnology and Nanomedicine: Start small, think big Materials Today: Proceedings, 5, 15492–15500 (Elsevier)

  • Kasprzak, M.M., Houdijk, J.G.M., Liddell, S., Davis, K., Olukosi, O.A., Kightley, S., White, G.A. and Wiseman, J., 2017. Rapeseed napin and cruciferin are readily digested by poultry. Journal of animal physiology and animal nutrition, 101, 658–666 (Germany)

  • Khalil, W.A., El-Harairy, M.A., Zeidan, A.E.B. and Hassan, M.A.E., 2019. Impact of selenium nano-particles in semen extender on bull sperm quality after cryopreservation. Theriogenology, 126, 121–127 (United States)

  • Kim, J.S., Kuk, E., Yu, K.N., Kim, J.-H., Park, S.J., Lee, H.J., Kim, S.H., Park, Y.K., Park, Y.H., Hwang, C.-Y., Kim, Y.-K., Lee, Y.-S., Jeong, D.H. and Cho, M.-H., 2007. Antimicrobial effects of silver nanoparticles. Nanomedicine : nanotechnology, biology, and medicine, 3, 95–101 (United States)

  • Kollenda, S.A., Klose, J., Knuschke, T., Sokolova, V., Schmitz, J., Staniszewska, M., Costa, P.F., Herrmann, K., Westendorf, A.M., Fendler, W.P. and Epple, M., 2020. In vivo biodistribution of calcium phosphate nanoparticles after intravascular, intramuscular, intratumoral, and soft tissue administration in mice investigated by small animal PET/CT. Acta biomaterialia, 109, 244–253 (England)

  • Krishna, V.D., Wu, K., Su, D., Cheeran, M.C.J., Wang, J.-P. and Perez, A., 2018. Nanotechnology: Review of concepts and potential application of sensing platforms in food safety. Food microbiology, 75, 47–54 (England)

  • Kumar, B. and Smita, K., 2017. Scope of nanotechnology in nutraceuticals In:, Nanotechnology Applications in Food, (Elsevier), 43–63

  • Lee, K.T., 2010. Quality and safety aspects of meat products as affected by various physical manipulations of packaging materials. Meat science, 86, 138–150 (England)

  • Lekshmi, M., Ammini, P., Kumar, S. and Varela, M.F., 2017. The Food Production Environment and the Development of Antimicrobial Resistance in Human Pathogens of Animal Origin. Microorganisms, 5

  • Leon, L., Chung, E.J. and Rinaldi, C., 2020. Chapter 1 - A brief history of nanotechnology and introduction to nanoparticles for biomedical applications In:, E. J. Chung , L. Leon , and C. B. T.-N. for B. A. Rinaldi (eds), Micro and Nano Technologies, (Elsevier), 1–4

  • Lowry, G. V, Avellan, A. and Gilbertson, L.M., 2019. Opportunities and challenges for nanotechnology in the agri-tech revolution Nature Nanotechnology, 14, 517–522

    Article  CAS  Google Scholar 

  • Lucignani, G. and Bombardieri, E., 2004. Molecular imaging: seeing the invisible beyond the “hot spot”. The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 48, 1–3 (Italy)

  • Maina, T.W., Grego, E.A., Boggiatto, P.M., Sacco, R.E., Narasimhan, B. and McGill, J.L., 2020. Applications of Nanovaccines for Disease Prevention in Cattle

  • Maurya, V.K., Bashir, K. and Aggarwal, M., 2020. Vitamin D microencapsulation and fortification: Trends and technologies. The Journal of steroid biochemistry and molecular biology, 196, 105489 (England)

  • McClements, D.J., 2020. Nanotechnology Approaches for Improving the Healthiness and Sustainability of the Modern Food Supply. ACS omega, 5, 29623–29630

    Article  CAS  Google Scholar 

  • Meena, N., Sahni, Y., Thakur, D. and Singh, R., 2018. Applications of nanotechnology in veterinary Vet World, 3, 477–480

    Google Scholar 

  • Mikuš, T., Marzel, R. and Mikuš, O., 2020. Early weaning: new insights on an ever-persistent problem in the dairy industry. The Journal of dairy research, 87, 88–92 (England)

  • Monerris, M.J., Arévalo, F.J., Fernández, H., Zon, M.A. and Molina, P.G., 2012. Integrated electrochemical immunosensor with gold nanoparticles for the determination of progesterone Sensors and Actuators B: Chemical, 166, 586–592 (Elsevier)

  • Morehead, M.S. and Scarbrough, C., 2018. Emergence of global antibiotic resistance Prim Care, 45, 467–484

    PubMed  Google Scholar 

  • Morin-Crini, N., Lichtfouse, E., Torri, G. and Crini, G., 2019. Applications of chitosan in food, pharmaceuticals, medicine, cosmetics, agriculture, textiles, pulp and paper, biotechnology, and environmental chemistry Environmental Chemistry Letters, 17, 1667–1692 (Springer)

  • Moyer, T.J., Zmolek, A.C. and Irvine, D.J., 2016. Beyond antigens and adjuvants: formulating future vaccines. The Journal of clinical investigation, 126, 799–808

    Article  Google Scholar 

  • Mukherjee, R., Patra, M., Dutta, D., Banik, M. and Basu, T., 2016. Tetracycline-loaded calcium phosphate nanoparticle (Tet-CPNP): Rejuvenation of an obsolete antibiotic to further action. Biochimica et biophysica acta, 1860, 1929–1941 (Netherlands)

  • Muktar, Y., Bikila, T. and Keffale, M., 2015. Application of nanotechnology for animal health and production improvement: a review World Appl Sci J, 33, 1588–1596

    Google Scholar 

  • Muller, R.H. and Keck, C.M., 2004. Challenges and solutions for the delivery of biotech drugs--a review of drug nanocrystal technology and lipid nanoparticles. Journal of biotechnology, 113, 151–170 (Netherlands)

  • Mustafa, F. and Andreescu, S., 2020. Nanotechnology-based approaches for food sensing and packaging applications RSC Advances, 10, 19309–19336 (Royal Society of Chemistry)

  • Nandedkar, T.D., 2009. Nanovaccines: recent developments in vaccination Journal of Biosciences, 34, 995–1003

  • Neculai-Valeanu, A.S., Ariton, A.M., Mădescu, B.M., Rîmbu, C.M. and Creangă, Ş., 2021. Nanomaterials and Essential Oils as Candidates for Developing Novel Treatment Options for Bovine Mastitis

  • Nile, S.H., Baskar, V., Selvaraj, D., Nile, A., Xiao, J. and Kai, G., 2020. Nanotechnologies in Food Science: Applications, Recent Trends, and Future Perspectives Nano-Micro Letters, 12, 45

    Article  CAS  Google Scholar 

  • Nordly, P., Madsen, H.B., Nielsen, H.M. and Foged, C., 2009. Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators. Expert opinion on drug delivery, 6, 657–672 (England)

  • O’Sullivan, M., Butler, S.T., Pierce, K.M., Crowe, M.A., O’Sullivan, K., Fitzgerald, R. and Buckley, F., 2020. Reproductive efficiency and survival of Holstein-Friesian cows of divergent Economic Breeding Index, evaluated under seasonal calving pasture-based management. Journal of dairy science, 103, 1685–1700 (United States)

  • Odhiambo, J.F., DeJarnette, J.M., Geary, T.W., Kennedy, C.E., Suarez, S.S., Sutovsky, M. and Sutovsky, P., 2014. Increased conception rates in beef cattle inseminated with nanopurified bull semen. Biology of reproduction, 91, 97 (United States)

  • Ognik, K., Kozłowski, K., Stępniowska, A., Szlązak, R., Tutaj, K., Zduńczyk, Z. and Jankowski, J., 2019. The effect of manganese nanoparticles on performance, redox reactions and epigenetic changes in turkey tissues. Animal : an international journal of animal bioscience, 13, 1137–1144 (England)

  • Öztürk-Atar, K., Eroğlu, H., Gürsoy, R.N. and Çaliş, S., 2019. Current advances in nanopharmaceuticals Journal of nanoscience and nanotechnology, 19, 3686–3705 (American Scientific Publishers)

  • Palumbo, B., Buresta, T., Nuvoli, S., Spanu, A., Schillaci, O., Fravolini, M.L. and Palumbo, I., 2014. SPECT and PET serve as molecular imaging techniques and in vivo biomarkers for brain metastases. International journal of molecular sciences, 15, 9878–9893

    Article  Google Scholar 

  • Patil, S., Kore, K. and Kumar, P., 2009. Nanotechnology and its applications in Veterinary and Animal Science Veterinary World, 2

  • Petruska, P., Capcarova, M. and Sutovsky, P., 2014. Antioxidant supplementation and purification of semen for improved artificial insemination in livestock species Turkish Journal of Veterinary and Animal Sciences, 38, 643–652 (The Scientific and Technological Research Council of Turkey)

  • Qi, L., Xu, Z., Jiang, X., Hu, C. and Zou, X., 2004. Preparation and antibacterial activity of chitosan nanoparticles. Carbohydrate research, 339, 2693–2700 (Netherlands)

  • Rajeshkumar, S. and Naik, P., 2018. Synthesis and biomedical applications of Cerium oxide nanoparticles - A Review. Biotechnology reports (Amsterdam, Netherlands), 17, 1–5

    CAS  Google Scholar 

  • Ramachandraiah, K., Han, S.G. and Chin, K.B., 2015. Nanotechnology in meat processing and packaging: potential applications - a review Asian-Australasian journal of animal sciences, 28, 290–302 (Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST))

  • Ramasamy, M., Kim, S., Lee, S.S. and Yi, D.K., 2016. Recyclable Photo-Thermal Nano-Aggregates of Magnetic Nanoparticle Conjugated Gold Nanorods for Effective Pathogenic Bacteria Lysis. Journal of nanoscience and nanotechnology, 16, 555–561 (United States)

  • Ravichandran, R., 2010. Nanotechnology Applications in Food and Food Processing: Innovative Green Approaches, Opportunities and Uncertainties for Global Market International Journal of Green Nanotechnology: Physics and Chemistry, 1, P72–P96 (Taylor & Francis)

  • Reddy, K.E., Jeong, J., Baek, Y.-C., Oh, Y.K., Kim, M., So, K.M., Kim, M.J., Kim, D.W., Park, S.K. and Lee, H.-J., 2017. Early weaning of calves after different dietary regimens affects later rumen development, growth, and carcass traits in Hanwoo cattle. Asian-Australasian journal of animal sciences, 30, 1425–1434

    Article  CAS  Google Scholar 

  • Reljic, R. and González-Fernández, Á., 2019. Editorial: Nanoparticle Vaccines Against Infectious Diseases.

  • Rivelli Bixquert, M.I., 2019. The effect of rumen-protected protein and amino acids, and genetic milk casein polymorphism on dairy cows’ performance (University of Illinois at Urbana-Champaign)

  • Sahoo, S.K. and Labhasetwar, V., 2003. Nanotech approaches to drug delivery and imaging. Drug discovery today, 8, 1112–1120 (England)

  • Salamanca-Buentello, F. and Daar, A.S., 2021. Nanotechnology, equity and global health Nature Nanotechnology, 1–4 (Nature Publishing Group)

  • Scott, N.R., 2007. Nanoscience in veterinary medicine Veterinary research communications, 31, 139–144 (Springer)

  • Sekhon, B., Sekhon, B. and Saluja, V., 2011. Nanovaccines-An overview International Journal of Pharmaceutical Frontier Research, 1, 101–109

    CAS  Google Scholar 

  • Shafiq, M., Anjum, S., Hano, C., Anjum, I. and Abbasi, B.H., 2020. An Overview of the Applications of Nanomaterials and Nanodevices in the Food Industry. Foods (Basel, Switzerland), 9

  • Shahin, M.A., Khalil, W.A., Saadeldin, I.M., Swelum, A.A.-A. and El-Harairy, M.A., 2020. Comparison between the Effects of Adding Vitamins, Trace Elements, and Nanoparticles to SHOTOR Extender on the Cryopreservation of Dromedary Camel Epididymal Spermatozoa. Animals : an open access journal from MDPI, 10

  • Sharma, A., Sharma, N., Kumari, A., Lee, H.-J., Kim, T. and Tripathi, K.M., 2020. Nano-carbon based sensors for bacterial detection and discrimination in clinical diagnosis: A junction between material science and biology Applied Materials Today, 18, 100467 (Elsevier)

  • Soh, J.H., Chan, H.-M. and Ying, J.Y., 2020. Strategies for developing sensitive and specific nanoparticle-based lateral flow assays as point-of-care diagnostic device Nano Today, 30, 100831 (Elsevier)

  • Sutovsky, P. and Lovercamp, K., 2010. Molecular markers of sperm quality. Society of Reproduction and Fertility supplement, 67, 247–256 (England)

  • Taouzinet, L., Fatmi, S., Lahiani-Skiba, M., Skiba, M. and Iguer-Ouada, M., 2021. Encapsulation Nanotechnology in Sperm Cryopreservation: Systems Preparation Methods and Antioxidants Enhanced Delivery CryoLetters, 42, 1–12 (Cryoletters)

  • Tatli Seven, P., Seven, I., Gul Baykalir, B., Iflazoglu Mutlu, S. and Salem, A.Z.M., 2018. Nanotechnology and nano-propolis in animal production and health: An overview Italian Journal of Animal Science, 17, 921–930 (Taylor & Francis)

  • Taylor, T.M., Davidson, P.M., Bruce, B.D. and Weiss, J., 2005. Liposomal nanocapsules in food science and agriculture. Critical reviews in food science and nutrition, 45, 587–605 (United States)

  • Thekkethil, A.J., Nair, R. and Madhavan, A., 2019. The Role Of Nanotechnology In Food Safety:A Review In:, 2019 International Conference on Computational Intelligence and Knowledge Economy (ICCIKE),

  • Travan, A., Pelillo, C., Donati, I., Marsich, E., Benincasa, M., Scarpa, T., Semeraro, S., Turco, G., Gennaro, R. and Paoletti, S., 2009. Non-cytotoxic silver nanoparticle-polysaccharide nanocomposites with antimicrobial activity. Biomacromolecules, 10, 1429–1435 (United States)

  • Turos, E., Reddy, G.S.K., Greenhalgh, K., Ramaraju, P., Abeylath, S.C., Jang, S., Dickey, S. and Lim, D. V, 2007. Penicillin-bound polyacrylate nanoparticles: restoring the activity of beta-lactam antibiotics against MRSA. Bioorganic & medicinal chemistry letters, 17, 3468–3472

    Article  CAS  Google Scholar 

  • Ummi, A.S. and Siddiquee, S., 2019. Nanotechnology applications in food: opportunities and challenges in food industry Nanotechnology: Applications in Energy, Drug and Food, 295–308 (Springer)

  • Underwood, C. and van Eps, A.W., 2012. Nanomedicine and veterinary science: the reality and the practicality. Veterinary journal (London, England : 1997), 193, 12–23 (England)

  • Van Zanten, H.H.E., Herrero, M., Van Hal, O., Röös, E., Muller, A., Garnett, T., Gerber, P.J., Schader, C. and De Boer, I.J.M., 2018. Defining a land boundary for sustainable livestock consumption. Global change biology, 24, 4185–4194 (England)

  • Vassallo, A., Silletti, M.F., Faraone, I. and Milella, L., 2020. Nanoparticulate Antibiotic Systems as Antibacterial Agents and Antibiotic Delivery Platforms to Fight Infections Journal of Nanomaterials, 2020 (Hindawi)

  • Wang, X.F., Zhang, S.L., Zhu, L.Y., Xie, S.Y., Dong, Z., Wang, Y. and Zhou, W.Z., 2012. Enhancement of antibacterial activity of tilmicosin against Staphylococcus aureus by solid lipid nanoparticles in vitro and in vivo. Veterinary journal (London, England : 1997), 191, 115–120 (England)

  • Wilczewska, A.Z., Niemirowicz, K., Markiewicz, K.H. and Car, H., 2012. Nanoparticles as drug delivery systems Pharmacological reports, 64, 1020–1037 (Elsevier)

  • Yang, D., 2021. Application of Nanotechnology in the COVID-19 Pandemic International journal of nanomedicine, 16, 623–649 (Dove)

  • Yang, T. and Duncan, T. V, 2021. Challenges and potential solutions for nanosensors intended for use with foods. Nature nanotechnology, 16, 251–265 (England)

  • Yimer, M., Bikila, T. and Bezabih, M., 2015. Application of Nanotechnology for Animal Health and Production Improvement: A Review 33, 1588–1596

    Google Scholar 

  • You, C.-C., Miranda, O.R., Gider, B., Ghosh, P.S., Kim, I.-B., Erdogan, B., Krovi, S.A., Bunz, U.H.F. and Rotello, V.M., 2007. Detection and identification of proteins using nanoparticle-fluorescent polymer “chemical nose” sensors. Nature nanotechnology, 2, 318–323 (England)

  • Youssef, F.S., El-Banna, H.A., Elzorba, H.Y. and Galal, A.M., 2019. Application of some nanoparticles in the field of veterinary medicine International journal of veterinary science and medicine, 7, 78–93 (Taylor & Francis)

  • Zahin, N., Anwar, R., Tewari, D., Kabir, M.T., Sajid, A., Mathew, B., Uddin, M.S., Aleya, L. and Abdel-Daim, M.M., 2019. Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery Environmental Science and Pollution Research, 1–18 (Springer)

  • Zhang, L., Pornpattananangku, D., Hu, C.-M.J. and Huang, C.-M., 2010. Development of nanoparticles for antimicrobial drug delivery. Current medicinal chemistry, 17, 585–594 (United Arab Emirates)

Download references

Author information

Authors and Affiliations

Authors

Contributions

AA and MI gave the main idea. AA and YRK made the layout. AA, HAS, KH, and AHR wrote manuscript. MS and ON worked on tables. AG, MAN, and MZZ did formatting. AIM and IA did proof reading. All the authors revised and finalized the article.

Corresponding author

Correspondence to Ahmad Ali.

Ethics declarations

Ethics approval

This review does not involve any human or animal testing.

Consent to participate

Not applicable.

Consent for publication

Not applicable.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ali, A., Ijaz, M., Khan, Y.R. et al. Role of nanotechnology in animal production and veterinary medicine. Trop Anim Health Prod 53, 508 (2021). https://doi.org/10.1007/s11250-021-02951-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11250-021-02951-5

Keywords

Navigation