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Efficacy of phytobiotic and toxin binder feed additives individually or in combination on the growth performance, blood biochemical parameters, intestinal morphology, and microbial population in broiler chickens exposed to aflatoxin B1

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Abstract

This experiment was conducted to investigate the effects of phytobiotic and antifungal feed additives on the growth performance, blood parameters, intestinal morphology, and cecal microbiota activity of broiler chickens under aflatoxicosis challenge. A total of 250 one-day-old Ross 308 broiler chicks (mixed sex) were reared on the littered floor with a completely randomized design by five treatments and five replicates for 35 days. Treatments included positive control (without AFB1), negative control-AFB1 (1 ppm), negative control-phytobiotic (Entex, 0.5 kg/t), negative control-Mycofix Plus (0.5 kg/t), and negative control-phytobiotic + Mycofix Plus. Dietary phytogenic and toxin binder improved body weight gain and feed conversion ratio of broiler chickens (p<0.05). Serum concentration of AST increased in broilers which received AFB1 without additives, while the blood concentration of total protein decreased (p<0.05). In jejuna morphometric indices, it was observed that the broiler chickens fed phytobiotic additive in combination with toxin binder had a greater villus length and crypt depth (p<0.05). Dietary treatments had no significant effect on the cecal microbial population in broiler chickens. In conclusion, the present results indicated that phytobiotic and toxin binder supplement improved growth performance and intestinal morphology of broiler chickens exposed to AFB1 challenge.

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Authors and Affiliations

  1. Department of Animal Science, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

    Pouya Tavangar, Shahabodin Gharahveysi, Vahid Rezaeipour & Mehrdad Irani

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  1. Pouya Tavangar
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  2. Shahabodin Gharahveysi
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  3. Vahid Rezaeipour
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  4. Mehrdad Irani
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Contributions

All the authors contributed to the study conception and design. Data collection was done by Pouya Tavangar. Data analysis and manuscript preparation were performed by Vahid Rezaeipour, Shahabodin Gharahveysi, and Mehrdad Irani. All the authors edited, read, and approved the final manuscript.

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Correspondence to Vahid Rezaeipour.

Ethics declarations

The study was conducted at a commercial poultry farm (Qaemshahr, Mazandaran province, north of Iran). All broiler chickens’ care and use procedures were approved by the Department of Animal Science, Islamic Azad University (Qaemshahr branch, Qaemshahr, Iran).

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Tavangar, P., Gharahveysi, S., Rezaeipour, V. et al. Efficacy of phytobiotic and toxin binder feed additives individually or in combination on the growth performance, blood biochemical parameters, intestinal morphology, and microbial population in broiler chickens exposed to aflatoxin B1. Trop Anim Health Prod 53, 335 (2021). https://doi.org/10.1007/s11250-021-02778-0

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