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Assessment on bioactive role of Moringa oleifera leaves as anthelmintic agent and improved growth performance in goats

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Abstract

The aim of this study was to evaluate the bioactive effect of Moringa oleifera leaves hydroalcoholic extract as a dietary feed additive on helminths load and growth performances of goats. Initially, the availability of bioactive compounds in M. oleifera hydroalcoholic extract was analysed using gas chromatography-mass spectrometry (GC-MS), which showed the presence of heneicosane (35.69%), 1,2-benzenedicarboxylic acid (22.89%), heptacosane (18.26%), pentatriacontane (4.77%), and hexadecanoic acid ethyl ester (3%) as predominant compounds in the leaves extract. The anthelmintic effect of M. oleifera extract (0 and 60 mL of extract animal-1) was evaluated against disparate nematodes using standard methodology. M. oleifera leaves extract exhibited significant (P = 0.002) anthelmintic activities against Trichuris sp. and Ostertagia sp. with reduced counts of eggs. A completely randomized experiment of 3 treatments comprised of 10 goats in each treatment was designed for the growth performance study. Treatments used in the present experiment were as follows: treatment 1 (T1), 0 mL of extract animal-1; treatment 2 (T2), 30 mL of extract animal-1; and treatment 3 (T3), 60 mL of extract animal-1. Growth performance parameters (body weight, daily weight gain, and feed intake values) of goats fed varied concentrations of M. oleifera extract were estimated as per standard protocols. The T2 and T3 groups’ goats offered significant (P < 0.05) increment in body weight. Daily weight gain of the T2 and T3 groups’ goats was also increased. Group T3 exhibited maximum feed intake value of 588, 678, 652, and 678 g d-1 at 0, 30, 45, and 60 days, respectively. Feed conversion efficiency was increased for T2 and T3 groups’ goats versus T1. Findings of this study concluded that M. oleifera hydroalcoholic extract can be used not only as an effective anthelmintic agent against disparate nematodes but also as a prominent feed additive to improve growth performances of goats.

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Funding

This work was financed by the project #UAEM 4304/2017/CI of the Universidad Autónoma del Estado de México, México.

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Authors and Affiliations

  1. Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, México

    Juan Pedraza-Hernández, Mona M. M. Y. Elghandour, Alberto Barbabosa-Pliego & Abdelfattah Z. M. Salem

  2. Research Department of Plant Biology and Biotechnology, Loyola College, Nungambakkam, Chennai, 600034, India

    Ameer Khusro

  3. Forestry and Wood Technology Department, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria, 21545, Egypt

    Mohamed Z. M. Salem

  4. Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Gurrero, Chilpancingo, México

    Luis M. Camacho-Diaz

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  1. Juan Pedraza-Hernández
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Contributions

JPH, AZMS, and MMMYE conceived and designed research. AZMS, MMMYE Supervisores. JPH, ABP, MMMYE and AZMS conducted experiments. MZMS Analysis the bioactive compounds of the M. oleifera leaves. JPH, LMCD, and ABP Helped in parasitology analysis and contributed new reagents or analytical tools. JPH, LMCD, and AZMS analysed data. JPH, MMMYE, AK, and AZMS wrote the manuscript. AK, AZMS, and MMMYE edited and revised the manuscript as well as prepared it for journal submission. All authors read and approved the manuscript.

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Correspondence to Abdelfattah Z. M. Salem.

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Pedraza-Hernández, J., Elghandour, M.M.M.Y., Khusro, A. et al. Assessment on bioactive role of Moringa oleifera leaves as anthelmintic agent and improved growth performance in goats. Trop Anim Health Prod 53, 318 (2021). https://doi.org/10.1007/s11250-021-02745-9

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