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Evaluating the effectiveness of two bovine mastitis vaccines and their influences on oxidant and antioxidant capacities of milk

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Abstract

The aim of the current study was to investigate the efficacy of two commercial mastitis vaccines (Startvac® and Mastivac®) and their influence on oxidant and antioxidant capacities of milk samples in a dairy farm. A total of 165 Holstein dairy cows were recruited into the study and were divided into Startvac®, Mastivac®, and control groups. The effects on the incidence and severity of clinical mastitis cases, duration of treatment, infection status, bacteriologic culture, somatic cell count, 5-thio-2-nitrobenzoic acid assay and ferric reducing antioxidant power assay, incidence of metritis and endometritis, and milk yield were evaluated within the first 90 days of lactation. The incidence of clinical mastitis was not significantly different among groups. The mean SCCs during the first, second, and third months of lactation did not differ significantly. The percentage of cured cows did not differ significantly. TNB and FRAP assays were used to know whether or not vaccination against mastitis has an effect on oxidant and antioxidant capacity of milk samples, which did not differ significantly. In conclusion, we observed no significant difference in the abovementioned variables. However, it is possible that applying mastitis vaccines within the specific conditions may have positive effects considering the results of previous studies.

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Abbreviations

TNB:

Thio-nitrobenzoate

FRAP

Ferric reducing antioxidant power

SCC

Somatic cell count

TOC

Total oxidant capacity

TAC

Total antioxidant capacity

S. aureus

Staphylococcus aureus

E. coliEscherichia coli

CNS

Coagulase-negative staphylococci

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Acknowledgments

The authors would like to gratefully acknowledge Mr. A. Kargar for his assistance in this project; also, Startvac® and Mastivac® vaccines were kind gifts of Sorur Fajr Co. and Nikan Pakhsh Behparvar companies (Tehran, Iran), respectively.

Funding

This work was supported by the Ferdowsi University of Mashhad (Grant number 3/39422, December/20/2015). Funding was allocated to collection, analysis and interpretation of data.

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Authors and Affiliations

  1. Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

    Niloufar Tashakkori, Babak Khoramian, Mohamad Heidarpour & Nima Farzaneh

  2. Department of Clinical Sciences, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

    Mehran Farhoodi Moghadam

  3. Quds Razavi Industrial Animal Husbandry Institute, Mashhad, Iran

    Komeil Mashayekhi

Authors
  1. Niloufar Tashakkori
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  2. Babak Khoramian
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  3. Mehran Farhoodi Moghadam
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  4. Mohamad Heidarpour
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  5. Komeil Mashayekhi
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  6. Nima Farzaneh
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Correspondence to Babak Khoramian.

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Tashakkori, N., Khoramian, B., Farhoodi Moghadam, M. et al. Evaluating the effectiveness of two bovine mastitis vaccines and their influences on oxidant and antioxidant capacities of milk. Trop Anim Health Prod 52, 1493–1501 (2020). https://doi.org/10.1007/s11250-019-02156-x

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