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Assessment of Awareness about Antibiotic Resistance and Practices Followed by Veterinarians for Judicious Prescription of Antibiotics: An Exploratory Study in Eastern Haryana Region of India

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Abstract

The rise of antibiotic resistance and its global outreach has recently become a subject of increasing importance in veterinary research with an objective to reduce the load of antibiotic resistance in dairy farming practices. The present study was designed to analyze antibiotic prescriptions by veterinarians and to evaluate the appropriateness of prescribing behavior in consistent with prudent use of antibiotics. A total of 48 veterinarians were selected randomly from government Veterinary hospitals constituting a total of 48 veterinarians as respondents. The study revealed that most of prescriptions corresponded sound to prudent use of antibiotic and its treatment guidelines. To assess their awareness about antibiotic resistance and its related veterinary practices, an exclusively Awareness Index of antibiotic resistance was developed. It was observed that antibiotics were prescribed in initial encounter of diagnosis; thus, antibiotic conservation practices were found lacking. The ethical awareness of veterinarians was found lacking to establish valid veterinary-client relationship and ensure active involvement of stakeholders. This study largely looks into this angle by unearthing the drug prescribing behavior in order to shape the interdisciplinary research on this biological and profoundly social issue.

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References

  • Alvan, G., Edlund, C. and Heddini, A., 2011. The global need for effective antibiotics—a summary of plenary presentations. Drug Resistance Updates, 14(2), 70–76.

    Article  PubMed  Google Scholar 

  • Anonymous, 2011. Annual Report, 2010–2011. National Dairy Research Institute, Karnal India, (2011). (www.ndri.res.in).

  • Ashley, E.A., Lubell, Y., White, N.J. and Turner, P., 2011. Antimicrobial susceptibility of bacterial isolates from community acquired infections in Sub-Saharan Africa and Asian low and middle income countries. Tropical Medicine & International Health, 16(9), 1167–1179.

    Article  Google Scholar 

  • Avorn, J. and Solomon, D.H., 2000. Cultural and economic factors that (mis) shape antibiotic use: the nonpharmacologic basis of therapeutics. Annals of internal medicine, 133(2), 128–135.

    Article  CAS  PubMed  Google Scholar 

  • Bengtsson, B. and Greko, C., 2014. Antibiotic resistance—consequences for animal health, welfare, and food production. Upsala journal of medical sciences, 119(2), 96–102.

    Article  PubMed  PubMed Central  Google Scholar 

  • Boucher, H.W., Talbot, G.H., Bradley, J.S., Edwards, J.E., Gilbert, D., Rice, L.B., Scheld, M., Spellberg, B. and Bartlett, J., 2009. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clinical infectious diseases, 48(1), 1–12.

    Article  PubMed  Google Scholar 

  • Cars, O., Högberg, L.D., Murray, M., Nordberg, O., Sivaraman, S., Lundborg, C.S., So, A.D. and Tomson, G., 2008. Meeting the challenge of antibiotic resistance. Bmj, 337, 1438.

    Article  Google Scholar 

  • De Bryne, N., Atkinson, J., Pokludová, L., Borriello, S.P. and Price, S., 2013. Factors influencing antibiotic prescribing habits and use of sensitivity testing amongst veterinarians in Europe. The Veterinary Record, 173(19), 475.

    Article  Google Scholar 

  • Dean, W.R., McIntosh, W.A., Scott, H.M. and Barling, K.S., 2011. The Role of Trust and Moral Obligation in Beef Cattle Feed-lot Veterinarians’ Contingent Adoption of Antibiotic Metaphylaxis Recommendations. International Journal of Sociology of Agriculture & Food, 18(2).

  • Derks, M., van de Ven, L.M., van Werven, T., Kremer, W.D. and Hogeveen, H., 2012. The perception of veterinary herd health management by Dutch dairy farmers and its current status in the Netherlands: A survey. Preventive veterinary medicine, 104(3–4), 207–215.

    Article  PubMed  Google Scholar 

  • F.V.E. Veterinarians Care for Animals and People: How to Use Antimicrobials Responsibly: Advice for Veterinarians. Brussels: Federation of Veterinarians of Europe, 2012. http://www.fve.org.

    Google Scholar 

  • Gelband, H. and Delahoy, H., 2014. Policies to Address Antibiotic Resistance in Low-and Middle-Income Countries: National and International Action on Antimicrobial Resistance. The Center for Disease Dynamics, Economics, and Policy.

  • Gelband, H., Molly Miller, P., Pant, S., Gandra, S., Levinson, J., Barter, D., White, A. and Laxminarayan, R., 2015. The state of the world’s antibiotics 2015. Wound Healing Southern Africa, 8(2), 30–34.

    Google Scholar 

  • Gibbons, J.F., Boland, F., Buckley, J.F., Butler, F., Egan, J., Fanning, S., Markey, B.K. and Leonard, F.C., 2013. Influences on antimicrobial prescribing behaviour of veterinary practitioners in cattle practice in Ireland. Veterinary Record, 172(1), 14–14.

    Article  CAS  PubMed  Google Scholar 

  • Gjelstad, S., Straand, J., Dalen, I., Fetveit, A., Strøm, H. and Lindbæk, M., 2011. Do general practitioners’ consultation rates influence their prescribing patterns of antibiotics for acute respiratory tract infections? Journal of antimicrobial chemotherapy, 66(10), 2425–2433.

    Article  CAS  PubMed  Google Scholar 

  • Global Antibiotic Resistance Partnership (GARP) - India Working Group, Ganguly NK, Arora NK, Chandy SJ, Fairoze MN, Gill JPS, et al. Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res. 2011 Sep; 134:281–94.

  • Gray, J., 2006. CHANGING PHYSICIAN PRESCRIBING BEHAVIOUR A CSCP LECTURE PRESENTED AT THE 2005 CANADIAN THERAPEUTICS CONGRESS.

  • Gwyther, C.L., Williams, A.P., Golyshin, P.N., Edwards-Jones, G. and Jones, D.L., 2011. The environmental and biosecurity characteristics of livestock carcass disposal methods: A review. Waste Management, 31(4), 767–778.

    Article  PubMed  Google Scholar 

  • Hulscher, M.E., Grol, R.P. and van der Meer, J.W., 2010. Antibiotic prescribing in hospitals: a social and behavioural scientific approach. The Lancet infectious diseases, 10(3), 167–175.

    Article  PubMed  Google Scholar 

  • Jan, J.S., McIntosh, W.A., Dean, W. and Scott, H.M., 2012. Predictors of differences in the perception of antimicrobial resistance risk in the treatment of sick, at-risk, and high-risk feedlot cattle. Preventive veterinary medicine, 106(1), 24–33.

    Article  PubMed  Google Scholar 

  • Jansen, J. and Lam, T.J., 2012. The role of communication in improving udder health. Veterinary Clinics: Food Animal Practice, 28(2), 363–379.

    Google Scholar 

  • Kakkar, M., Walia, K., Vong, S., Chatterjee, P., & Sharma, A., 2017. Antibiotic resistance and its containment in India. BMJ: British Medical Journal (Online), 358.

  • Klerkx, L. and Jansen, J., 2010. Building knowledge systems for sustainable agriculture: supporting private advisors to adequately address sustainable farm management in regular service contacts. International Journal of Agricultural Sustainability, 8(3), 148–163.

    Article  Google Scholar 

  • Koningstein, M., van der Bij, A.K., de Kraker, M.E., Monen, J.C., Muilwijk, J., de Greeff, S.C., Geerlings, S.E., Leverstein-van Hall, M.A. and ISIS-AR Study Group, 2014. Recommendations for the empirical treatment of complicated urinary tract infections using surveillance data on antimicrobial resistance in the Netherlands. PLoS One, 9(1), 86634.

  • Landers, T. F., Cohen, B., Wittum, T. E., & Larson, E. L., 2012. A review of antibiotic use in food animals: perspective, policy, and potential. Public health reports, 127(1), 4–22.

    Article  PubMed  PubMed Central  Google Scholar 

  • Laxminarayan, R. and Chaudhury, R.R., 2016. Antibiotic resistance in India: drivers and opportunities for action. PLoS medicine, 13(3), 1001974.

    Article  Google Scholar 

  • Laxminarayan, R., Duse, A., Wattal, C., Zaidi, A.K., Wertheim, H.F., Sumpradit, N., Vlieghe, E., Hara, G.L., Gould, I.M., Goossens, H. and Greko, C., 2013. Antibiotic resistance—the need for global solutions. The Lancet infectious diseases, 13(12), 1057–1098.

    Article  PubMed  Google Scholar 

  • Marshall B.M. and Levy S.B., 2011. Food animals and antimicrobials: impacts on human health. Clinical microbiology reviews 24, 718–733.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mathew A.G, Cissell R. and Liamthong S., 2007. Antibiotic resistance in bacteria associated with food animals: a United States perspective of livestock production. Foodborne pathogens and disease 4, 115–133.

    Article  CAS  PubMed  Google Scholar 

  • National Research Council, 2001. Strategies That Influence Cost Containment in Animal Research Facilities. National Academies Press.

  • O.I.E. Standards and guidelines can be found in the Terrestrial Animal Health Code (chapters 6.6., 6.7., 6.8., 6.9. and 6.10. and in the Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, 2012. (Guideline 2.1.). http://www.oie.int

  • Polk RE, Fishman NO. Antimicrobial stewardship. In: Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett's Principle and Practice of Infectious diseases. 7 th ed. Philadelphia: Elsevier Churchill Livingstone; 2010. p. 677-85

    Chapter  Google Scholar 

  • Prescott, J.F., 2008. Antimicrobial use in food and companion animals. Animal Health Research Reviews, 9(2), 127–133.

    Article  PubMed  Google Scholar 

  • Pulcini, C., Wencker, F., Frimodt-Møller, N., Kern, W.V., Nathwani, D., Rodríguez-Baño, J., Simonsen, G.S., Vlahović-Palčevski, V., Gyssens, I.C., Jacobs, F. and Peetermans, W., 2015. European survey on principles of prudent antibiotic prescribing teaching in undergraduate students. Clinical Microbiology and Infection, 21(4), 354–361.

    Article  CAS  PubMed  Google Scholar 

  • Raymond, M.J., Wohrle, R.D. and Call, D.R., 2006. Assessment and promotion of judicious antibiotic use on dairy farms in Washington State. Journal of dairy science, 89(8), 3228–3240.

    Article  CAS  PubMed  Google Scholar 

  • Regula, G., Torriani, K., Gassner, B., Stucki, F. and Müntener, C.R., 2009. Prescription patterns of antimicrobials in veterinary practices in Switzerland. Journal of antimicrobial chemotherapy, 63(4), 805–811.

    Article  CAS  PubMed  Google Scholar 

  • Sabuncu, E., David, J., Bernède-Bauduin, C., Pépin, S., Leroy, M., Boëlle, P.Y., Watier, L. and Guillemot, D., 2009. Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002–2007. PLoS medicine, 6(6), 1000084.

    Article  Google Scholar 

  • Sarraf-Yazdi, S., Sharpe, M., Bennett, K.M., Dotson, T.L., Anderson, D.J. and Vaslef, S.N., 2012. A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit. journal of surgical research, 176(2), e73-e78.

    Article  PubMed  Google Scholar 

  • Schultz, K.K., Strait, E.L., Erickson, B.Z. and Levy, N., 2012. Optimization of an antibiotic sensitivity assay for Mycoplasma hyosynoviae and susceptibility profiles of field isolates from 1997 to 2011. Veterinary microbiology, 158(1–2), 104–108.

    Article  CAS  PubMed  Google Scholar 

  • Schwarz, S., Kehrenberg, C. and Walsh, T.R., 2001. Use of antimicrobial agents in veterinary medicine and food animal production. International journal of antimicrobial agents, 17(6), 431–437.

    Article  CAS  PubMed  Google Scholar 

  • Sharma, C., Rokana, N., Chandra, M., Singh, B.P., Gulhane, R.D., Gill, J.P.S., Ray, P., Puniya, A.K. and Panwar, H., 2018. Antimicrobial resistance: its surveillance, impact, and alternative management strategies in dairy animals. Frontiers in veterinary science, 4, 237.

    Article  PubMed  PubMed Central  Google Scholar 

  • Simpson, S.A., Wood, F. and Butler, C.C., 2006. General practitioners’ perceptions of antimicrobial resistance: a qualitative study. Journal of Antimicrobial Chemotherapy, 59(2), 292–296.

    Article  PubMed  CAS  Google Scholar 

  • Speksnijder, D.C., Jaarsma, A.D.C., Van Der Gugten, A.C., Verheij, T.J. and Wagenaar, J.A., 2015. Determinants associated with veterinary antimicrobial prescribing in farm animals in the Netherlands: a qualitative study. Zoonoses and public health, 62, 39–51.

    Article  PubMed  Google Scholar 

  • Srivastava, R.K., Chaudhury, R.R., Bramhachari, S.K., Singh, S., Guleria, R., Sinha, A., Gupta, U., Kakkar, M., Rodrigues, C., Wattal, C. and Kotwani, A., 2011. National policy for containment of antimicrobial resistance India. Directorate General of Health Services, Ministry of Health and Family Welfare, Nirman Bhawan, New Delhi.

    Google Scholar 

  • Summers, A.O., 2002. Generally overlooked fundamentals of bacterial genetics and ecology. Clinical Infectious Diseases, 34(Supplement_3), S85-S92.

    Article  CAS  PubMed  Google Scholar 

  • Teuber M., 2001. Veterinary use and antibiotic resistance. Current opinion in microbiology 4, 493–499.

    Article  CAS  PubMed  Google Scholar 

  • Travasso, C., 2016. India draws a red line under antibiotic misuse. BMJ: British Medical Journal (Online), 352.

  • Unnikrishnan, V., Bhavadassan, M.K., Nath, B.S. and Ram, C., 2005. Chemical residues and contaminants in milk: A review. The Indian Journal of Animal Sciences, 75(5).

  • Vandeweerd, J.M., Vandeweerd, S., Gustin, C., Keesemaecker, G., Cambier, C., Clegg, P., Saegerman, C., Reda, A., Perrenoud, P. and Gustin, P., 2012. Understanding veterinary practitioners’ decision-making process: implications for veterinary medical education. Journal of veterinary medical education, 39(2), 142–151.

    Article  PubMed  Google Scholar 

  • Ventola, C.L., 2015. The antibiotic resistance crisis: part 2: management strategies and new agents. Pharmacy and Therapeutics, 40(5), 344.

    PubMed  PubMed Central  Google Scholar 

  • Williams, A., Mathai, A.S. and Phillips, A.S., 2011. Antibiotic prescription patterns at admission into a tertiary level intensive care unit in Northern India. Journal of pharmacy & bioallied sciences, 3(4), 531.

    Article  Google Scholar 

  • World Health Organization, 2014. World malaria report 2014. World Health Organization.

  • World Health Organization, 2015. Investing to overcome the global impact of neglected tropical diseases: third WHO report on neglected tropical diseases 2015 (Vol. 3). World Health Organization.

    Google Scholar 

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  1. National Dairy Research Institute, Karnal, Haryana, 132 001, India

    Vikash Kumar, Jancy Gupta & H. R. Meena

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  1. Vikash Kumar
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  2. Jancy Gupta
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  3. H. R. Meena
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Correspondence to Vikash Kumar.

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Kumar, V., Gupta, J. & Meena, H.R. Assessment of Awareness about Antibiotic Resistance and Practices Followed by Veterinarians for Judicious Prescription of Antibiotics: An Exploratory Study in Eastern Haryana Region of India. Trop Anim Health Prod 51, 677–687 (2019). https://doi.org/10.1007/s11250-018-1742-0

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