Abstract
Antibody response produced by Newcastle disease virus (NDV, strain I-2) when given orally through oiled rice to chickens was determined. Serum samples were collected before and at a weekly interval for 28 days after vaccination and tested for haemagglutination inhibition (HI) antibody to NDV. The results showed 7 days after vaccination HI antibody titre log2 was 3.8. Moreover, 14 and 28 days after vaccination HI antibody titre log2 reached 6.5 and 8.0, respectively. All unvaccinated chickens were negative to NDV antibody throughout the study. Significant finding from the present study is that 7 days after vaccination chickens had produced protective antibody against NDV; this is in contrast to previous studies. Therefore, I-2 vaccine coated on the oiled rice is efficacious as it protects chickens from challenge with NDV.
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Abbreviations
- EID50 :
-
median embryo infectious dose
- HA:
-
haemagglutination
- HI:
-
haemagglutination-inhibition
- NDV:
-
Newcastle disease virus
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Wambura, P. N., 2008. Oral vaccination of chickens against Newcastle disease with I-2 vaccine coated on oiled rice. Tropical Animal Health and Production.
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Wambura, P.N. Oral vaccination of chickens against Newcastle disease with I-2 vaccine coated on oiled rice. Trop Anim Health Prod 41, 205–208 (2009). https://doi.org/10.1007/s11250-008-9176-8
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DOI: https://doi.org/10.1007/s11250-008-9176-8