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Immunohistochemical staining for tilapia and human insulin demonstrates that a tilapia transgenic for humanized insulin is a mosaic

Transgenic Research volume 17, pages 991–992 (2008)Cite this article

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Fig. 1

References

  • Pohajdak B, Mansour M, Hrytsenko O, Conlon JM, Dymond LC, Wright JR Jr (2004) Production of transgenic tilapia with Brockman bodies secreting [desThrB30] human insulin. Transgenic Res 13:313–323

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  • Snowdon J (2003) Generation of a mouse monoclonal antibody against tilapia (Oreochromis niloticus) insulin: Application to histology and enzyme-linked immunosorbent assay. M.Sc. thesis, Dalhousie University, Halifax, NS

  • Yang H, Morrison CM, Conlon JM, Laybolt K, Wright JR Jr (1999) Immunocytochemical characterization of the pancreatic islet cells of the tilapia (Oreochromis niloticus). Gen Comp Endocrinol 114:47–56

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Acknowledgement

Funded by the Juvenile Diabetes Research Foundation.

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Affiliations

  1. Department of Pathology & Laboratory Medicine (Calgary Laboratory Services) and the Julia McFarlane Diabetes Research Centre, Faculty of Medicine, University of Calgary, Room C410, Diagnostic & Scientific Centre, 9, 3535 Research Road NW, Calgary, AB, Canada, T2L 2K8

    James R. Wright Jr

  2. Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada

    Jaime Snowdon

  3. Department of Biology, Dalhousie University, Halifax, NS, Canada

    Olga Hrytsenko & Bill Pohajdak

  4. IWK Health Centre, Halifax, NS, Canada

    Carol M. Morrison

Authors
  1. James R. Wright Jr
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  2. Jaime Snowdon
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  3. Olga Hrytsenko
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  4. Carol M. Morrison
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  5. Bill Pohajdak
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Corresponding author

Correspondence to James R. Wright Jr.

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Wright, J.R., Snowdon, J., Hrytsenko, O. et al. Immunohistochemical staining for tilapia and human insulin demonstrates that a tilapia transgenic for humanized insulin is a mosaic. Transgenic Res 17, 991–992 (2008). https://doi.org/10.1007/s11248-008-9183-6

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  • DOI: https://doi.org/10.1007/s11248-008-9183-6

Keywords

  • Site Directed Mutagenesis
  • Human Insulin
  • Teleost Fish
  • Tight Cluster
  • Immunoperoxidase Staining